Development and Optimization of Raft-Forming Formulation of H2blockers
MANSI MANOJ BHOSALE,
PRAMODKUMAR J SHIROTE
Abstract:Objective: The present research work is focused to develop in situ raft gel of Nizatidine. sodium alginate (SA) is one of the critical components for the development in situ raft system.
Methods: The formulation was prepared using polymers such as SA and gellan gum. The formulations were subjected to evaluation characteristics such as pH, in vitro gelling capacity, viscosity, gel strength, and in vitro release studies.
Results: The pH of all the prepared batches was found in the range of 6.4–7.2 for S1–S9, and… Show more
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