Development and optimization of a method for determining betaine and trigonelline in the fruits of Lycium species by using solid‐phase extraction combined with high‐performance liquid chromatography–diode array detector
Abstract:Betaine is an essential nutrient for humans and a source of methyl donors for methionine and S-adenosylmethionine formation, and it is used as a biomarker for pharmacological activities and to evaluate the quality of Lycium species and common foods.However, because of its special structural features, poor ultraviolet-chromophore, and high polarity, the existing methods for betaine extraction and quantification cannot provide higher extraction efficiency, better sensitivity, or resolution degree. A simple, fast… Show more
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