Development and internal validation of a multivariable risk prediction model for severe rebound pain after foot and ankle surgery involving single-shot popliteal sciatic nerve block

Jen, Tim T. H.; Ke, Janny Xue Chen; Wing, Kevin; Denomme, Justine; McIsaac, Daniel I.; Huang, Shih-Chieh; Ree, Ronald M; Prabhakar, Christopher; Schwarz, Stephan; Yarnold, Cynthia H.

doi:10.1016/j.bja.2022.03.030

Cited by 9 publications

(12 citation statements)

References 35 publications

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“…Peripheral nerve block is an important part of regional anesthesia and has been widely used in kinds of surgeries, especially orthopedics. 2 , 4 , 24 One of the risk factors of rebound pain has been reported to be blocking the regions of relatively dense nerve distribution, such as brachial plexus and popliteal space. 4 , 6 We suggest that future studies of rebound pain would better base on these findings.…”

Section: Discussionmentioning

confidence: 99%

Current Status and Global Trend of Rebound Pain After Regional Anesthesia: A Bibliometric Analysis

Zhou,

Jiang,

Miao

et al. 2024

LRA

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Purpose Rebound pain after regional anesthesia, a common phenomenon when the analgesic effect wears off, has been recognized in the last a few years. The aim of this study is to analyze the status and tendency of this area in a macroscopic perspective. Methods Bibliometric analysis is the primary methodology of this study. Literature retrieval was conducted in Web of Science (WoS) Core Collection. WoS, Excel, VOSviewer and CiteSpace were employed to do the analyses and visualization. Parameters were analyzed, such as publications, citations, journals, and keywords, etc. Results In total, 70 articles in the past 10 years were identified eligible. Most articles (14 pieces) were published in 2021, followed by 2022 and 2023 with 13 articles. Researchers come from 134 institutions and 20 countries. Huang Jung-Taek, Hallym College, and USA are the most productive author, institution and country, respectively. The articles were mainly published on the top journals of anesthesiology, orthopedics and surgery. The topic of these articles is primarily about the clinical issues of rebound pain. Peripheral nerve block, brachial plexus block and femoral nerve block are the activist keywords in the area, while perioperative management, fracture surgery and outcome may become hotpots in the next years. Conclusion Our results show that the study of rebound pain after regional anesthesia starts relatively late and is in upward tendency, future studies can focus on the perioperative management and outcomes of fracture patients, and the definition and mechanism of rebound pain after regional anesthesia.

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Section: Discussionmentioning

confidence: 99%

Current Status and Global Trend of Rebound Pain After Regional Anesthesia: A Bibliometric Analysis

Zhou,

Jiang,

Miao

et al. 2024

LRA

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“…Bedenkt man, dass die Zeit, in der dieses Phänomen aufzutreten scheint, regelhaft nicht in anästhesiologischer Verantwortung ist [3], lässt sich nachvollziehen, dass Autoren aus USA eher organisatorische Lücken als ein biologisches Phänomen vermuten [4]. So ist es auch nicht wirklich verwunderlich, wenn Regressionsmodelle, in denen organisatorische Defizite unberücksichtigt bleiben [5], nicht in der Lage sind, das Auftreten vorherzusagen.…”

Section: Kommentarunclassified

Regionalanästhesie: Opioidsparende Wirkung trotz Rebound-Phänomen

2024

Journal Club AINS

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“…The sample size for the study was calculated using SAS version 9.1. According to the published literature, 14 the incidence of rebound pain is about 50%. We aimed to reduce rebound pain by 25% in group IV compared to group C. We calculated that 58 patients per group were needed (power = 80%, α = 0.05), but to allow for the incidence of patient withdrawals, we planned for 65 patients per group.…”

Section: Study Design and Participantsmentioning

confidence: 99%

The Effects of Intravenous Dexamethasone on Rebound Pain After Nerve Block in Patients with Ankle Fracture: A Randomized Controlled Trial

Gao¹,

Li²,

Yu³

et al. 2023

JPR

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Purpose A single-injection nerve block provides excellent analgesia in a short time, but rebound pain after the nerve block disappears has attracted researchers’ attention. The aim of this study is to evaluate the effect of intravenous dexamethasone on rebound pain after adductor canal block (ACB) and popliteal sciatic nerve block in patients with ankle fracture. Methods We recruited 130 patients with ankle fractures scheduled for open reduction and internal fixation (ORIF), each of whom received ACB and popliteal sciatic nerve block. Patients were divided into two groups: C (ropivacaine only) and IV (ropivacaine with intravenous dexamethasone). The primary outcome was the incidence of rebound pain. Secondary outcomes included the following: pain scores at 6 h (T 1 ), 12 h (T 2 ), 18 h (T 3 ), 24 h (T 4 ), and 48 h (T 5 ) after operation; duration of the nerve block; number of presses of the analgesia pump and rescue analgesic consumption in the three-day postoperative period; quality of recovery scale (QoR-15 score); postoperative sleep quality; satisfaction of patients; and levels of serum inflammatory markers (IL-1β, IL-6, and TNF-α) six hours after surgery. Results Compared with group C, the incidence of rebound pain in group IV was significantly reduced, and the duration of nerve block was extended by approximately nine hours ( P <0.05). Moreover, patients in group IV had significantly lower pain scores at T 2 -T 4 , lower levels of serum inflammatory markers (IL-1β, IL-6, and TNF-α), higher QoR-15 score two days after the operation, and satisfactory sleep quality the night after surgery ( P <0.05). Conclusion Intravenous dexamethasone can reduce the rebound pain after adductor block and sciatic popliteal nerve block in patients with ankle fracture surgery, prolong the duration of nerve block, and improve the quality of early postoperative recovery.

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Development and internal validation of a multivariable risk prediction model for severe rebound pain after foot and ankle surgery involving single-shot popliteal sciatic nerve block

Cited by 9 publications

References 35 publications

Current Status and Global Trend of Rebound Pain After Regional Anesthesia: A Bibliometric Analysis

Current Status and Global Trend of Rebound Pain After Regional Anesthesia: A Bibliometric Analysis

Regionalanästhesie: Opioidsparende Wirkung trotz Rebound-Phänomen

The Effects of Intravenous Dexamethasone on Rebound Pain After Nerve Block in Patients with Ankle Fracture: A Randomized Controlled Trial

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