Development and initial validation of a modified Sinclair scale for female pattern hair loss in men

Kerkemeyer, Karolina Louisa Suzanna; Poa, Janina Eliza; Carvalho, Lara Trindade de; Eisman, Samantha; Imperial, Ivan Christian Vj; Sinclair, Rodney; Bhoyrul, Bevin

doi:10.1016/j.jaad.2021.06.004

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…Since all patients with FAPD had female pattern hair loss (FPHL) type appearance, the severity of alopecia was decided by the Sinclair scale designed specifically for FPHL. This 5‐point grading system enables reliable detection of subtle changes in hair density 6 . For patients whose severity is situated between two grades, the average of the two grades was used.…”

Section: Methodsmentioning

confidence: 99%

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Clinicopathological characteristics of fibrosing alopecia in a pattern distribution: a single‐center, retrospective study

Wei,

Ni,

Huang

et al. 2023

Int J Dermatology

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BackgroundFibrosing alopecia in a pattern distribution (FAPD) is a distinct entity of primary cicatricial alopecia (PCA), mimicking diffuse hair loss of androgenetic alopecia (AGA) with trichoscopic and histopathologic features of both AGA and lichen planopilaris (LPP).MethodsClinical, demographic, and histopathological data of 20 FAPD patients were retrospectively collected.ResultsAll patients presented with female pattern hair loss with a median Sinclair grade of 3. Trichoscopic findings revealed hair diameter variability (20/20), perifollicular erythema (mild 7/20, moderate 11/20, severe 2/20), peripilar casts (none 2/20, mild 12/20, moderate 5/20, severe 1/20), and loss of follicular ostia (+12/20, ±7/20, −1/20). Histopathologic examination revealed perifollicular lymphocytic infiltration at the infundibulum or isthmus level and an increase of vellus‐like hairs. All cases showed interface dermatitis with concentric perifollicular lamellar fibrosis and follicular scars. Infundibular or isthmic infiltration of mast cells was found.ConclusionsThe uniqueness of our study lies in perifollicular mast cells and discovering that the young population is at higher risk than previously thought. Clinicopathological features of FAPD were identified, filling the void of much‐needed details for FAPD diagnosis tailored to the Chinese population.

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Section: Methodsmentioning

confidence: 99%

“…This 5point grading system enables reliable detection of subtle changes in hair density. 6 For patients whose severity is situated between two grades, the average of the two grades was used.…”

Section: Clinical Assessmentsmentioning

confidence: 99%

Clinicopathological characteristics of fibrosing alopecia in a pattern distribution: a single‐center, retrospective study

Wei,

Ni,

Huang

et al. 2023

Int J Dermatology

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Investigation of oral finasteride enhanced occipital hair diameter index in different types of male androgenetic alopecia

Wang,

Yang,

Lin

et al. 2023

Journal of the American Academy of Dermatology

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Variants of female pattern hair loss in men

Awad,

Sharma,

Bhoyrul

2024

Clinical and Experimental Dermatology

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Female pattern hair loss (FPHL) presents with hair thinning on the mid-frontal scalp and crown with retention of the anterior hairline. In a proportion women with FPHL, there is a gradual decrease in hair density from the vertex to the frontal region, resulting in a triangular or “Christmas tree” pattern.1 Despite what its name may suggest, FPHL can also affect men.2 However, the Christmas tree pattern has only been used to describe frontal accentuation of hair loss in women. The aim of our study was to determine the patterns of hair loss of FPHL in men.

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Development and initial validation of a modified Sinclair scale for female pattern hair loss in men

Cited by 3 publications

References 5 publications

Clinicopathological characteristics of fibrosing alopecia in a pattern distribution: a single‐center, retrospective study

Clinicopathological characteristics of fibrosing alopecia in a pattern distribution: a single‐center, retrospective study

Investigation of oral finasteride enhanced occipital hair diameter index in different types of male androgenetic alopecia

Variants of female pattern hair loss in men

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