Development and in-vitro evaluation of mucoadhesive gastroretentive matrix tablets of cephalexin

Yadav, Vishal

doi:10.9790/3008-0742531

Cited by 2 publications

(1 citation statement)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The well-mixed powder was compressed by direct compression technique. [ 7 ] Tablets were compressed on Shakti multi station punching machine using 13 mm flat punches, with the hardness of 5 kg/cm 2 .…”

Section: Methodsmentioning

confidence: 99%

Novel sustained release and swellable gastroretentive dosage form for ciprofloxacin hydrochloride

Gaikwad¹,

Yadav

Gaikwad³

2014

Int J Pharma Investig

View full text Add to dashboard Cite

Introduction:The present study aims at developing a gastroretentive swellable and floating matrix tablet formulation of ciprofloxacin hydrochloride (HCl) for the effective treatment of infections caused by susceptible organisms. Ciprofloxacin HCl is a fluoroquinoline antibiotic drug. Ciprofloxacin HCl is more stable in acidic medium and it has a narrow absorption window which is sited at the stomach and proximal portions of the small intestine, so it covers the required criteria for selection of drug for gastroretentive dosage form.Materials and Methods:Ciprofloxacin HCl gastroretentive tablets were formulated by using direct compression method and different grades of hydroxypropyl methylcellulose as suspending and stabilizing agent (polymer), sodium starch glycolate (SSG), crospovidone as disintegrates, sodium bicarbonate as alkalizing agent and magnesium stearate as lubricant.Results:The tablets were evaluated for post compression parameters. All the parameters were within the pharmacopoeial limits.Conclusion:The in vitro dissolution studies showed that the drug release was fast in formulations F2, F4 and F6 containing SSG as super disintegrant when compared with all other formulations. In SEM study of F2 formulation shows maximum swelling and porosity observed after 12 h. Hence, formulation F2 shows the best formulation among the six formulations containing different binders and super disintegrants.

show abstract

Section: Methodsmentioning

confidence: 99%

Novel sustained release and swellable gastroretentive dosage form for ciprofloxacin hydrochloride

Gaikwad¹,

Yadav

Gaikwad³

2014

Int J Pharma Investig

View full text Add to dashboard Cite

show abstract

Natural Lip Balm

Sankpal¹,

Kadam²,

Aswale³

et al. 2022

IJARSCT

View full text Add to dashboard Cite

Cosmetics are unbelievably in demand since historical time. These days people prefers naturally derived cosmetic products. Cosmetic plays a important role in today’s life style. Along all cosmetic products, Natural lip balm preprations are most widely used to increase the beauty of lips and add glamour touch and shine to the beauty. Lip balms provides a natural way to promote healthy and moisturized lips. Coloring lips is the ancient practice to increase the beauty of lips and to give shine to the face. Current cosmetic lip products are based on use of toxic chemical ingredients with various adverse effect. That’s why it leads to study natural ingredients used to production of natural lip balm. This article reviews on the natural ingredients used for natural lip balm along with their advantages and disadvantages.

show abstract

Development and in-vitro evaluation of mucoadhesive gastroretentive matrix tablets of cephalexin

Cited by 2 publications

References 5 publications

Novel sustained release and swellable gastroretentive dosage form for ciprofloxacin hydrochloride

Novel sustained release and swellable gastroretentive dosage form for ciprofloxacin hydrochloride

Natural Lip Balm

Contact Info

Product

Resources

About