Abstract:Background:
Paclitaxel (PTX) is a potent anticancer drug which is highly effective
against several cancers. Solid lipid nanoparticles (SLNs) loaded with anticancer
drugs can enhance its toxicity against tumor cells at low concentrations.
Objective:
To develop and characterize SLNs of PTX (PSLN) to enhance its toxicity
against cancerous cells.
Method:
The solubility of PTX was screened in various lipids. Solid lipid nanoparticles
of PTX (PSLN) were developed by hot homogenization method using Cutina H… Show more
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