Development and Implementation of Uplc-MS/MS Method for the Determination of Piperazine Residues in Pig Tissues
D. Yanovych,
M. Rydchuk,
S. Plotytsia
et al.
Abstract:The manuscript presents the results of the development and validation of UPLC-MS/MS method for the determination of piperazine residues in muscle and parenchymal tissues of pigs. Piperazine and its derivatives are well-known anthelmintic drugs used in human and veterinary medicine. Piperazine is a heterocyclic compound without any chromophore groups with a low molecular weight (86.1 g/mol), which makes its detection in biological samples by LC-MS/MS difficult. We have developed the confirmatory technique for t… Show more
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