Development and function of a natural reverse shoulder in a patient with thalidomide-induced dysmelia

Kimmeyer, Michael; Lehmann, Lars; Gerhardt, Christian; Schmalzl, Jonas

doi:10.1016/j.xrrt.2020.11.009

Cited by 3 publications

(3 citation statements)

References 13 publications

(14 reference statements)

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“…While reverse total shoulder joint arthroplasty is a common procedure in orthopaedic practice, a native reverse shoulder joint remains a rare phenomenon. To our knowledge, only two cases of a naturally occurring reverse shoulder joint have been reported in the literature [ 3 , 4 ]. It is important to highlight that both patients had congenital deformities, which included isolated congenital proximal humeral hypoplasia, and thalidomide-induced dysmelia, respectively.…”

Section: Discussionmentioning

confidence: 99%

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Anatomic Reversal of Shoulder Joint After Neck of Humerus Facture

Fernandes,

Chizooma,

Pearce

et al. 2024

Cureus

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We report on a singular case of a unique form of post-traumatic reversal of the humeral head after humeral neck fracture, in which the pattern of collapse resulted in the formation of a native reverse polarity shoulder. In essence, the humeral head became a socket, and the glenoid rounded to become a head with wellpreserved shoulder function. To our knowledge, this is the first case of an acquired shoulder deformity that bears a remarkable functional similarity to a prosthetic reverse polarity shoulder replacement.

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Section: Discussionmentioning

confidence: 99%

“…While the surgical procedure is widely accepted, little is known about the natural occurrence of a reverse shoulder joint. There are sparse reports of congenital reverse shoulder joint deformity in the literature [ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Anatomic Reversal of Shoulder Joint After Neck of Humerus Facture

Fernandes,

Chizooma,

Pearce

et al. 2024

Cureus

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“…The overall effect of this remodelling is to move the centre of rotation of the glenohumeral joint inferiorly and medially, optimizing the deltoid muscle lever arm for improved glenohumeral stability and function. These are the same principles that are harnessed in reverse geometry shoulder arthroplasty, and this pattern of change has been described as development of a ‘natural’ reverse shoulder replacement ( Kimmeyer et al., 2021 ) ( Figure 4 ).…”

Section: Age-related Problems In Upper Limb Thalidomide Embryopathymentioning

confidence: 97%

Thalidomide upper limb embryopathy – pathogenesis, past and present management and future considerations

Vargesson

Hooper

Giddins

et al. 2023

J Hand Surg Eur Vol

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This review article provides a comprehensive overview of thalidomide upper limb embryopathy including updates about its pathogenesis, a historical account of the management of the paediatric thalidomide patient, experience with management of the adult patient, as well as creating awareness about early onset age-related changes associated with limb differences. Despite its withdrawal from the market in November 1961, novel discoveries have meant thalidomide is licensed again and currently still in use to treat a variety of conditions, including inflammatory disorders and some cancers. Yet, if not used safely, thalidomide still has the potential to cause damage to the embryo. Recent work identifying thalidomide analogues that retain clinical benefits yet without the harmful effects are showing great promise. Understanding the problems thalidomide survivors face as they age can allow surgeons to support their unique healthcare issues and translate these principles of care to other congenital upper limb differences.

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