“…The prevalence of oral lesions is primarily determined through population-based studies, 14 , 15 , 16 , 17 , 18 or studies carried out in dental centers 19 , 20 , 21 or from oral pathology laboratories. 22 , 23 , 24 However, as no standardization in OOPML classification exists, with studies classifying OOPML by a lesion group (e.g., non-neoplastic lesions) 19 or by a specific disease (e.g., oral lesions in syphilis), 25 the reported OOPML frequencies are directly influenced. 26 , 27 , 28 Furthermore, the lack of systematic and standardized inclusion of oral cavity/oropharynx examination in the routine medical examination generates gaps in medical records, 29 , 30 and epidemiological surveys on oral health only provide information on diseases related to dental elements (e.g., caries, edentulism).…”