“…Therefore, underlying differences in the two groups may account for the observed differences in outcomes. Specifically, we did not evaluate other variables, such as comorbidities, the use of benzodiazepines or antiepileptics, or a history of falls before hospitalization, which are risk factors for falls in hospitalized patients [2,10,15,16], nor did we evaluate the effects of postoperative hemoglobin, which conceptually could be associated with falls, although this variable has not been identified as a risk factor in major fall risk assessment studies [2,10,15,16]. Second, while perioperative care for the patients was similar, based on standardized treatment algorithms and practice standards for all patients undergoing TKA at our institution, regardless of operating surgeon, the care was not identical; therefore, again other confounding unstudied variables may account for the differences in the fall rates between the two groups.…”