Development and evaluation of curcumin-loaded vesicular carriers: impact of formulation variables
Denitsa Momekova,
Viliana Gugleva,
Petar Petrov
Abstract:Vesicular carriers are a well-established approach to improving the technological and biopharmaceutical characteristics of the loaded cargo. The current manuscript is focused on the development and evaluation in a comparative aspect of two types of vesicles—ethosomes and transfersomes loaded with the phytoconstituent curcumin. The formulation variables affecting their physiochemical and cytotoxic properties are outlined as well. A series of ethosomes and transfersomes based on Lipoid S75 and ethanol, or edge a… Show more
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