Development and Evaluation of Bilayered Gastro-Retentive Tablet Containing Metforminhcl Sr and Pioglitazonehcl Ir

Vyas, Jigar; Upadhyay, Tulsi p; Vyas, H.; Dhameliya, Pankit; Thakkar, Nirali

doi:10.22270/jddt.v3i5.620

J. Drug Delivery Ther.

2013

DOI: 10.22270/jddt.v3i5.620

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Development and Evaluation of Bilayered Gastro-Retentive Tablet Containing Metforminhcl Sr and Pioglitazonehcl Ir

Jigar Vyas¹,

Tulsi p Upadhyay

H. Vyas³

et al.

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2024

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“…Medications such as corticosteroids are suggested for optional colonic release (Vyas and Khar 2006).…”

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confidence: 99%

Recent Advances in Gastro Retentive Drug Delivery Systems

Wafa,

Raihan,

Tyagi

2024

ejtas

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The issues with oral conventional dose forms can be resolved with the use of gastroretentive drug delivery systems (GRDDS). GRDDS is a way to prolong the stomach residence time, which allows for the release of drugs and the possibility of local or systemic effects in the upper gastrointestinal tract. To enhance treatment, some potent medications are employed with gastro-retentive dose forms for longer. By producing a high concentration of medication in the stomach that can be sustained for an extended amount of time, gastroretentive formulations (GRFs) greatly improve stomach pharmacotherapy. As a result, a wide range of dosage forms have been developed for medications that break down at alkaline pH but remain stable at acidic pH. Therefore, medications have limited absorption.

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“…Medications such as corticosteroids are suggested for optional colonic release (Vyas and Khar 2006).…”

mentioning

confidence: 99%

Recent Advances in Gastro Retentive Drug Delivery Systems

Wafa,

Raihan,

Tyagi

2024

ejtas

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Development and Evaluation of Bilayered Gastro-Retentive Tablet Containing Metforminhcl Sr and Pioglitazonehcl Ir

Cited by 1 publication

References 8 publications

Recent Advances in Gastro Retentive Drug Delivery Systems

Recent Advances in Gastro Retentive Drug Delivery Systems

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