Development and evaluation of a novel training program to build study staff skills in equitable and inclusive engagement, recruitment, and retention of clinical research participants

Cranfill, Jessica R.; Freel, Stephanie A.; Deeter, Christine; Snyder, Denise C.; Naggie, Susanna; Barrett, Nadine; Roberts, Jamie

doi:10.1017/cts.2022.456

Cited by 4 publications

(3 citation statements)

References 20 publications

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“…Figure 2 provides a high-level overview on moving this process forward. Reworking the competency-based job classifications provide an excellent starting point to tie together improved onboarding, training, on the job support, expansion of diversity and inclusion efforts ( Cranfill et al, 2022 ) and professional development ( Deeter et al, 2020 ). Establishing strong collaborations between clinical research leadership and HR will promote building a talented workforce supporting the quality and success of clinical trials.…”

Section: Discussionmentioning

confidence: 99%

Enhancing the clinical research workforce: a collaborative approach with human resources

Snyder,

Gaudaur,

Marchant

et al. 2024

Front. Pharmacol.

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Jobs for clinical research professionals (CRPs) have grown increasingly complex over the past 20+ years. This is due largely to additional administrative burden for investigators, study teams, sponsors, Clinical Research Organizations (CROs), and sites, particularly Academic Medical Centers (AMCs). Furthermore, National Institutes of Health (NIH) has reduced capacity to effectively fund research recognizing this is dependent on the overall congressional budget, which creates greater pressure for clinician scientists to secure external support. It is widely known clinical research will continue to become increasingly more complex for clinician scientists. This manuscript explores adoption of a clinical research competency-based job classification framework from the Joint Task Force for Clinical Trial Competency (JTFCTC) across several AMCs and the role of Human Resources (HR) in facilitating this process. This collaboration focuses on fostering successful projects tied to the business case in order to address equity and improve support for the clinical research enterprise.

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Section: Discussionmentioning

confidence: 99%

Enhancing the clinical research workforce: a collaborative approach with human resources

Snyder,

Gaudaur,

Marchant

et al. 2024

Front. Pharmacol.

Self Cite

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“…Rubio et al report women and members of underrepresented groups remain persistently underrepresented among principal investigators in the National Institute of Health's CTSA program while women have greater representation as participants in the career development and training programs, and non-White individuals are better represented in the training programs [10]. Manuscripts also describe the implementation of novel training curricula addressing structural racism and centering the lived experience of impacted people, as well as training and mentorship programs for URM students, early-career investigators, and clinical research professionals engaged in clinical research recruitment [11][12][13][14][15][16].…”

Section: Trainingmentioning

confidence: 99%

Laying the groundwork to make diversity, equity, and inclusion front and center in clinical and translational research

Egede

Ruiz

Mosley-Johnson

et al. 2023

J. Clin. Trans. Sci.

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“…5 Further upstream barriers facing clinicians include failure to prescreen patients for eligibility, biases about discussing trials as an option for treatment 18 and assumptions about a patient's treatment preferences. 19 At the health systems level, cancer treating facilities may face limited availability of clinical trials, restrictive eligibility criteria in available trials, 20 limited staffing and infrastructure capacity and capability, [21][22][23] ineffective patient screening and enrollment practices, 16,[24][25][26][27][28][29][30][31] or poor community engagement. 5,30 Across all potential barriers, however, there has been very little documentation of evidence showing what works to increase accrual.…”

Section: Introductionmentioning

confidence: 99%

Strategies for increasing accrual in cancer clinical trials: What is the evidence?

Michaels,

Weiss,

Sae‐Hau

et al. 2024

Cancer Medicine

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IntroductionDespite the importance of clinical trial participation among cancer patients, few participate—and even fewer patients from ethnic and racial minoritized groups. It is unclear whether suggested approaches to increase accrual are successful. We conducted a scoping review to identify evidence‐based approaches to increase participation in cancer treatment clinical trials that demonstrated clear increases in accrual. Notably, more stringent than other published reviews, only those studies with comparison data to measure a difference in accrual rates were included.MethodsWe searched PubMed/MEDLINE, Embase, CINAHL, and Web of Science for English‐language articles published from January 1, 2012, to August 8, 2022. Studies were included if they were conducted in the United States, described single or multicomponent interventions, and provided data to measure accrual relative to baseline levels or that compared accrual rates with other interventions.ResultsSixteen articles were included: six with interventions addressing patient barriers, two addressing provider barriers, seven describing institutional change, and one describing policy change. Key themes emerged, such as a focus on patient education, cultural competency, and building the capacity of clinics. Few studies provide comparative accrual data, making it difficult to identify with certainty any effective, evidence‐based approaches for increasing accrual. Some patient‐ and system‐level interventions studies showed modest increases in accrual primarily through pre‐post measurement.ConclusionDespite an extensive body of literature about the barriers that impede cancer treatment trial accrual, along with numerous recommendations for how to overcome these barriers, results reveal surprisingly little evidence published in the last 10 years on interventions that increase accrual relative to baseline levels or compared with other interventions. As clinical trials are a primary vehicle through which we improve cancer care, it is critical that evidence‐based approaches are used to inform all efforts to increase accrual. Strategies for increasing participation in cancer clinical trials must be developed and rigorously evaluated so that these strategies can be disseminated, participation in trials can increase and become more equitable, and trial results can become more generalizable.

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Development and evaluation of a novel training program to build study staff skills in equitable and inclusive engagement, recruitment, and retention of clinical research participants

Abstract: This version may be subject to change during the production process.

Cited by 4 publications

References 20 publications

Enhancing the clinical research workforce: a collaborative approach with human resources

Enhancing the clinical research workforce: a collaborative approach with human resources

Laying the groundwork to make diversity, equity, and inclusion front and center in clinical and translational research

Strategies for increasing accrual in cancer clinical trials: What is the evidence?

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