Development and Evaluation of a Phantom for Multi-Purpose Dosimetry in Intensity-Modulated Radiation Therapy

Jeong, Hae Sun; Han, Youngyih; Kum, Oyeon; Kim, Chan Hyeong; Park, Joo Hwan

doi:10.5516/net.2011.43.4.399

Cited by 7 publications

(5 citation statements)

References 11 publications

(14 reference statements)

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“…[15][16][17] we have developed an LEGO humanoid phantom to verify the quality of treatment and to implement some steps procedures of commission using flexible programmable devices with realtime capability. The robot was built using LEGO Mindstorms programmable EV3, adding an expansion set to the base core set.…”

Section: Phantom Constructionmentioning

confidence: 99%

Real-Time Lung Tumour Motion Modeling for Adaptive Radiation Therapy Using Lego Mindstorms

Guidi

Maffei

Ciarmatori

et al. 2015

J. Mech. Med. Biol.

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An anthropomorphic phantom was built using LEGO Mindstorms r and programmed in LabVIEW r for Adaptive Radiation Therapy (ART) purpose, to simulate the processes of breathing in the lung district during treatments. A thoracic cavity is prototyped by means of an 8 ribs apparatus and 2 artificial tumor masses, driven by intelligent brick LINUX r OS CPU. An optical surface tracking system (VisionRT r Þ and a QUASAR TM phantom allow correlation between physiological, robotic motion and surrogated signal. Patient's breathing phases are acquired instantaneously by InfraRed/UltraSound sensors. Through 4DCT images, tumor center of mass are individuated and tracked during respiration, to link internal-external organs motion. To quantify the degree of divergences due to dynamics organs deformation, a 4D function was obtained and simulated by our phantom. Sinusoidal signals (6, 10, 12, 15 and 17 Breaths per Minute-BPM) were used for evaluating and commissioning, thereby obtained a correlation coefficient (0.90-0.94) between QUASAR and LEGO. Validated on ideal conditions, phantom was tested in clinical practice. Breaths and CT study of 12 patients were analyzed. Fitting of real breath sinograms returned a mean R value of 0.94 (0.83-0.98) with best model performance achieved in signals with respiratory frequency less than 20 BPM. By using LEGO it is possible to reproduce real patients conditions and simulate normal and even abnormal behavior during the course of therapy, allowing spatial motion estimation.

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Section: Phantom Constructionmentioning

confidence: 99%

Real-Time Lung Tumour Motion Modeling for Adaptive Radiation Therapy Using Lego Mindstorms

Guidi

Maffei

Ciarmatori

et al. 2015

J. Mech. Med. Biol.

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“…Thus, a phantom designed for use in a kilovoltage energy range will be made of different materials from a phantom made for megavoltage usage. Several other materials have, however, been reportedly used by several other authors (Blomquist and Karlsson, 1998;da Rosa et al, 2010;Jeong et al, 2011;Senthilkumar and Ramakrishnan, 2011;Senthilkumar, 2014) for the various body tissue simulation. The basic properties considered in virtually all of them are the materials' physical density (ρ), electron density (ρ e ), and effective atomic number (z eff ), which is a combination of the materials' percentage elemental composition and their electron densities.…”

Section: Introductionmentioning

confidence: 99%

“…The basic properties considered in virtually all of them are the materials' physical density (ρ), electron density (ρ e ), and effective atomic number (z eff ), which is a combination of the materials' percentage elemental composition and their electron densities. Jeong et al (2011) used equations 1-2 to calculate the effective atomic number (z eff ) of the following materials for various tissue simulations: Polystyrene, polyethylene, polytetrafluoroethylene (PTFE), and polyurethane foam (PU-F).…”

Section: Introductionmentioning

confidence: 99%

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Investigation of the Suitability of Different Materials as Human Tissue Simulating Materials in Co-60 Radiation Energy Beam

Ogunsina,

Balogun,

Saidu

et al. 2023

USci

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Radiotherapy calibration for precise dose delivery traditionally relies on water phantom systems, but this approach poses challenges of heterogeneous corrections or the use of anthropomorphic phantoms which most underdeveloped nations find expensive. In this study, the suitability of some tissue simulating materials were investigated within the Co-60 photons energy range. This study explores the identification of locally sourced materials to simulate human tissue behavior in Co-60 energy beams. By considering effective atomic numbers and physical densities, we evaluate materials for simulating soft tissue, lung, and bone. Water, aluminum metal, and polystyrene (Styrofoam) were selected for simulating soft tissue, bone, and lung, respectively, due to their close radiological properties, availability, and affordability. This research provides valuable insights for resource-constrained regions aiming to improve radiotherapy calibration methods.

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“…Water-equivalent materials (with rED *1, such as thermoplastics and silicones) mimic the response of soft tissues (e.g., brain matter), 15,16 whereas bone-equivalent materials (rED *1.5-2, typical of highdensity polymers, such as polytetrafluoroethylene [PTFE]) mimic that of hard parts. 17,18 The design and fabrication of cerebral vascular phantoms using additive manufacturing for neurosurgery have already been reported in the literature. 13,[19][20][21][22] The most representative examples are mainly related to surgical aid applications (e.g., aneurysm clipping 20,23 ) as well as to diagnosis, 24,25 blood circulation analysis, 26,27 and patients' information purposes.…”

Section: Introductionmentioning

confidence: 99%

Additive Fabrication of a Vascular 3D Phantom for Stereotactic Radiosurgery of Arteriovenous Malformations

Legnani

Gallo

Pezzotta

et al. 2021

3D Printing and Additive Manufacturing

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In this study, an efficient methodology for manufacturing a realistic three-dimensional (3D) cerebrovascular phantom resembling a brain arteriovenous malformation (AVM) for applications in stereotactic radiosurgery is presented. The AVM vascular structure was 3D reconstructed from brain computed tomography (CT) data acquired from a patient. For the phantom fabrication, stereolithography was used to produce the AVM model and combined with silicone casting to mimic the brain parenchyma surrounding the vascular structure. This model was made with tissues-equivalent materials for radiology. The hollow vascular system of the phantom was filled with a contrast agent usually employed on patients for CT scans. The radiological response of the phantom was tested and compared with the one of the clinical case. The constructed model demonstrated to be a very accurate physical representation of the AVM and its vasculature and good morphological consistency was observed between the model and the patient-specific source anatomy. These results suggest that the proposed method has potential to be used to fabricate patient-specific phantoms for neurovascular radiosurgery applications and medical research.

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Development and Evaluation of a Phantom for Multi-Purpose Dosimetry in Intensity-Modulated Radiation Therapy

Cited by 7 publications

References 11 publications

Real-Time Lung Tumour Motion Modeling for Adaptive Radiation Therapy Using Lego Mindstorms

Real-Time Lung Tumour Motion Modeling for Adaptive Radiation Therapy Using Lego Mindstorms

Investigation of the Suitability of Different Materials as Human Tissue Simulating Materials in Co-60 Radiation Energy Beam

Additive Fabrication of a Vascular 3D Phantom for Stereotactic Radiosurgery of Arteriovenous Malformations

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