Development and deployment of a histopathology-based deep learning algorithm for patient prescreening in a clinical trial
Albert Juan Ramon,
Chaitanya Parmar,
Oscar M. Carrasco-Zevallos
et al.
Abstract:Accurate identification of genetic alterations in tumors, such as Fibroblast Growth Factor Receptor, is crucial for treating with targeted therapies; however, molecular testing can delay patient care due to the time and tissue required. Successful development, validation, and deployment of an AI-based, biomarker-detection algorithm could reduce screening cost and accelerate patient recruitment. Here, we develop a deep-learning algorithm using >3000 H&E-stained whole slide images from patients with advan… Show more
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