Development and Clinical Trial of Virtual Reality-Based Cognitive Assessment in People with Stroke: Preliminary Study

Abstract

Stroke and traumatic brain injury affect an increasing number of people, many of whom retain permanent damage in cognitive functions. Conventionally, cognitive function has been assessed by a paper-based neuropsychological evaluation. However these test environments differ substantially from everyday life. This problem can be overcome by using virtual reality (VR) to objectively evaluate behaviors and cognitive function in simulated daily activities. With our virtual shopping simulation, we compared people who had undergone a stroke with control participants in an immersive VR program that used a head-mounted display (HMD). We evaluated user satisfaction with the tests, complications, and the user interface. Significant differences were consistently found between the stroke group and the control group for the following tasks: stage 1 performance index, interaction error; stage 2 delayed recognition memory score, attention index; and stage 3 executive index (p < 0.001). Perceptive dysfunction, visuospatial dysfunction, level of computer experience, and level of education affected the performance of the stroke group. The frequency of complications in the stroke group, calculated using the cut-off score for the Simulator Sickness Questionnaire, was 9.6% for nausea, 41.9% for oculomotor complications, and 25.8% for disorientation. The frequency of complications between the stroke and control groups was not significantly different. Thirty-five percent of participants in the stroke group and 13% in the control group reported difficulties with using the joystick. This computer-generated VR-based cognitive test shows promise in assessing cognitive function in patients with stroke. More refinements are needed in the user interface and the projection methods.

Virtual reality-based therapy for the treatment of balance deficits in patients receiving inpatient rehabilitation for traumatic brain injury

“…[35,36] Despite the broad use of VR-based therapy for balance-focused rehabilitation in neurologically similar populations, the use of VR for the physical rehabilitation of patients with TBI has been limited, [35][36][37]97] with the majority of research focusing on cognitive rehabilitation. [31,[98][99][100][101][102][103][104][105][106] Applications of VR have sparsely been used for physical rehabilitation [37] and functional training, including completing kitchen activities, [32,98] using automatic teller machines, [107] driving [108][109][110] and wayfinding. [111] In regards to balance, VR has been investigated as a tool to assess deficits post injury in athletes with mild TBI, [112][113][114] and as a therapeutic technique to treat long-term balance deficits in patients more than six months post TBI.…”

Effects of Virtual Reality Treadmill Training on Balance and Balance Self-efficacy in Stroke Patients with a History of Falling

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Novel Virtual Reality Application in Field of Neurorehabilitation

“…Kang et al [35] showed that the frequency of virtual motion sickness was not significantly different between the normal group and the stroke group in the immersive VR experience using HMD. Motion sickness is an important factor that does not sustain the experience of VR and diminishes the sense of reality that plays an important role in VR experience.…”