Development and characterization of an electrochemical sensor for furosemide detection based on electropolymerized molecularly imprinted polymer

Kor, Kamalodin; Zarei, Kobra

doi:10.1016/j.talanta.2015.08.042

Cited by 88 publications

(20 citation statements)

References 24 publications

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“…Direct deposition of MIPs composed of poly(o-phenylenediamine) (PoPD) on gold electrodes has been employed for the preparation of sensors with high selectivity for furosemide [108] and atrazine [109]. Galvanostatic deposition of pyrrole in the presence of the antibiotic, sulfadimethoxine, was extensively studied by Turco et al [110].…”

Section: Biosensing Platforms Incorporating Electrosynthesized Molmentioning

confidence: 99%

Recent Advances in Electrosynthesized Molecularly Imprinted Polymer Sensing Platforms for Bioanalyte Detection

Crapnell

Hudson

Foster

et al. 2019

Sensors

181

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The accurate detection of biological materials has remained at the forefront of scientific research for decades. This includes the detection of molecules, proteins, and bacteria. Biomimetic sensors look to replicate the sensitive and selective mechanisms that are found in biological systems and incorporate these properties into functional sensing platforms. Molecularly imprinted polymers (MIPs) are synthetic receptors that can form high affinity binding sites complementary to the specific analyte of interest. They utilise the shape, size, and functionality to produce sensitive and selective recognition of target analytes. One route of synthesizing MIPs is through electropolymerization, utilising predominantly constant potential methods or cyclic voltammetry. This methodology allows for the formation of a polymer directly onto the surface of a transducer. The thickness, morphology, and topography of the films can be manipulated specifically for each template. Recently, numerous reviews have been published in the production and sensing applications of MIPs; however, there are few reports on the use of electrosynthesized MIPs (eMIPs). The number of publications and citations utilising eMIPs is increasing each year, with a review produced on the topic in 2012. This review will primarily focus on advancements from 2012 in the use of eMIPs in sensing platforms for the detection of biologically relevant materials, including the development of increased polymer layer dimensions for whole bacteria detection and the use of mixed monomer compositions to increase selectivity toward analytes.

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Section: Biosensing Platforms Incorporating Electrosynthesized Molmentioning

confidence: 99%

Recent Advances in Electrosynthesized Molecularly Imprinted Polymer Sensing Platforms for Bioanalyte Detection

Crapnell

Hudson

Foster

et al. 2019

Sensors

181

View full text Add to dashboard Cite

show abstract

“…As seen from Figure A, o‐PD oxidized to its dimer form at 0.4 V vs. Ag/AgCl described an anodic peak in the first scan. The current response of the anodic peak decreased during the successive cycles and almost disappeared at the end of polymerization since the formation of non‐conductive o‐PD film prevented redox couple ([Fe(CN) 6 ] 3−/4− ) from reaching to the surface of electrode . When the electropolymerization of o‐PD was achieved in the absence of MEL (Figure B), almost the same voltammetric behavior was observed in presence of MEL due to the electro‐inactivity of MEL in applied potential range.…”

Section: Resultsmentioning

confidence: 99%

Electrosynthesis of Molecularly Imprinted Poly‐o‐phenylenediamine on MWCNT Modified Electrode for Selective Determination of Meldonium

Güney

2019

Electroanalysis

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In this study, a molecularly imprinted polymer (MIP) was synthesized by electrochemical polymerization and used to construct an electrochemical sensor for determination of meldonium (MEL) selectively for the first time. The polymer film was generated by using o‐phenylenediamine (o‐PD) as a monomer on the surface of carboxylic acid functionalized multiwalled carbon nanotube (MWCNT) modified pencil rod electrode in the presence of MEL as a template. MEL imprinted (MEL‐imp) and non‐imprinted (N‐imp) polymer films and coated electrodes were characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), profilometry, electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Voltammetric measurements were carried out in a ferrocyanide/ferricyanide redox probe solution for MEL‐imp and N‐imp electrodes in the presence and absence of template molecule. The decrease in peak current of redox probe was linear with the concentration of MEL in the range of 0.1–5 μg/mL and the limit of detection (3 s/b) was found to be 0.066 μg/mL under optimized experimental conditions. The proposed sensor was successfully applied for selective determination of MEL in human urine sample with long term stability and good reproducibility.

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“…Instead of using the absolute current values, which might vary with the surface areas as well as the electrode congurations from electrode to electrode, a calibration curve was plotted between the relative current change (DI/I 0 ) and salbutamol concentration. 27,28 Here, DI ¼ I 0 À I C , where I 0 and I C are the current values when the concentration of salbutamol is 0 and C nM, respectively. As shown in Fig.…”

Section: Linear Range and Detection Limitmentioning

confidence: 99%

An electrochemical MIP sensor for selective detection of salbutamol based on a graphene/PEDOT:PSS modified screen printed carbon electrode

et al. 2018

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A sensitive electrochemical MIP sensor for salbutamol detection based on a graphene nanocomposite modified screen-printed carbon electrode was successfully demonstrated. Insertion of the graphene/ PEDOT:PSS layer prior to the MIP was aimed at enhancing the sensitivity of the sensor. Selection of a functional monomer was carried out using 1 H-NMR titration and a computational calculation was used to further investigate the template-monomer interactions. The MIP layer was constructed on top of the highly conductive nanocomposite by co-electropolymerization of 3-aminophenylboronic acid and o-phenylenediamine in the presence of salbutamol. Using differential pulse voltammetry under optimal conditions, a linear response in the range of 1 nM to 1.2 mM, with an exceptional detection limit of 100 pM (S/N ¼ 3) was obtained. The established sensor exhibited good reproducibility, reusability and stability. Additionally, good selectivity in discriminating salbutamol from other structurally related compounds could also be realized. Determination of salbutamol in real swine meat and feed samples was also successfully carried out with good recovery results.

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Development and characterization of an electrochemical sensor for furosemide detection based on electropolymerized molecularly imprinted polymer

Cited by 88 publications

References 24 publications

Recent Advances in Electrosynthesized Molecularly Imprinted Polymer Sensing Platforms for Bioanalyte Detection

Recent Advances in Electrosynthesized Molecularly Imprinted Polymer Sensing Platforms for Bioanalyte Detection

Electrosynthesis of Molecularly Imprinted Poly‐o‐phenylenediamine on MWCNT Modified Electrode for Selective Determination of Meldonium

An electrochemical MIP sensor for selective detection of salbutamol based on a graphene/PEDOT:PSS modified screen printed carbon electrode

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