Development and applications of a monoclonal antibody to a recombinant beak and feather disease virus (BFDV) capsid protein

Shearer, Patrick; Bonne, Nicolai; Clark, P.; Sharp, Margaret; Raidal, Shane R.

doi:10.1016/j.jviromet.2007.08.029

Cited by 13 publications

(3 citation statements)

References 21 publications

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“…Two chicks with subtle feather lesions and poor weight gain were euthanazed and histopathological examination of the visceral organs and skin performed. Sections of skin, spleen and visceral organs were tested by immunohistochemistry for BFDV according to established protocols 35 .…”

Section: Methodsmentioning

confidence: 99%

Evidence of a deep viral host switch event with beak and feather disease virus infection in rainbow bee-eaters (Merops ornatus)

Sarker

Moylan

Ghorashi

et al. 2015

Sci Rep

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Since the characterization of psittacine beak and feather disease (PBFD) in 1984, a wide range of avian circoviruses have been discovered with varying pathogenic effects amongst a diverse range of avian hosts. Until recently these circovirus species were thought to be restricted to within avian Orders such as the Psittaciformes for beak and feather disease virus (BFDV) and Columbiformes for pigeon circovirus with little evidence of cross-family transmission or replication. We report evidence of a naturally occurring novel host switch event with self-limiting BFDV infection in a group of rainbow bee-eaters (Merops ornatus) a species of Coraciiformes unrelated to parrots and not previously known to be susceptible to any avian circovirus. The outbreak highlights important and unexpected aspects of disease emergence and host-switching pertinent to other situations when viruses might cross species boundaries as well as the potential of avian circoviruses to infect disparate host species.

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Section: Methodsmentioning

confidence: 99%

Evidence of a deep viral host switch event with beak and feather disease virus infection in rainbow bee-eaters (Merops ornatus)

Sarker

Moylan

Ghorashi

et al. 2015

Sci Rep

Self Cite

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“…Formalin‐fixed skin was processed by routine histological methods, stained with haematoxylin and eosin and examined by light microscopy for the presence of characteristic inclusion bodies. BFDV infection was confirmed by immunohistochemistry (IHC) using primary monoclonal antibodies to recombinant BFDV capsid protein, and a horseradish peroxidase (HRP) conjugated secondary antibody analysis were performed on paraffin‐embedded skin sections. Briefly, 5‐μm sections of formalin‐fixed and paraffin‐embedded skin and other tissues were placed onto glass slides, de‐waxed and re‐hydrated with Tris buffer.…”

Section: Methodsmentioning

confidence: 99%

Beak and feather disease virus carriage by Knemidocoptes pilae in a sulphur‐crested cockatoo (Cacatua galerita)

Portas¹,

Jackson

Das

et al. 2017

Aust Veterinary J

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“…These include histology, electron microscopy, haemagglutination, [34][35] immunohistochemistry, [36] in situ hybridisation, [37] polymerase chain reaction (PCR), [38] duplex shuttle PCR, [39] real-time PCR, [40] PCR followed by high-resolution melting curve analysis, [15][20] and swarm primer-applied loop-mediated isothermal amplification (sLAMP). [41] The serological detection of anti-BFDV antibodies has been conducted by haemagglutination inhibition [34][42] and Enzyme-Linked Immunosorbent Assay (ELISA) [36] . So far, the standard PCR-based assay has been used most frequently (>49%) to screen BFDV between 1984 and July 2015.…”

Section: Diagnosismentioning

confidence: 99%

Beak and feather disease virus: biology and resultant disease

Sarker¹,

Forwood²,

Raidal³

2020

Wiki J Sci

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The beak and feather disease virus (BFDV) causes psittacine beak and feather disease, an often chronic and fatal disease in psittacine birds. The virus most commonly infects psittacine birds, but is also capable of infecting nonpsittacine bird species in Australasia. The virus induces an immunosuppressive condition with chronic symmetrical irreversible loss of feather, as well as beak and claw deformities eventually leading to death. No specific treatment is currently commercially available for infected birds; however, a combination of quarantine and hygiene control, diagnostic testing and enhancing flock adaptive immunity is recommended to provide the most effective and sustainable control. Recent structural determination of BFDV capsid protein provides insights into the different assemblies that can be formed from one of the smallest known DNA viruses.

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Development and applications of a monoclonal antibody to a recombinant beak and feather disease virus (BFDV) capsid protein

Cited by 13 publications

References 21 publications

Evidence of a deep viral host switch event with beak and feather disease virus infection in rainbow bee-eaters (Merops ornatus)

Evidence of a deep viral host switch event with beak and feather disease virus infection in rainbow bee-eaters (Merops ornatus)

Beak and feather disease virus carriage by Knemidocoptes pilae in a sulphur‐crested cockatoo (Cacatua galerita)

Beak and feather disease virus: biology and resultant disease

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