Development and application of an electronic treatment register: a system for enumerating populations and monitoring treatment during mass drug administration

Oswald, William E.; Kennedy, David S.; Farzana, Jasmine; Kaliappan, Saravanakumar Puthupalayam; Atindegla, Eloïc; Houngbégnon, Parfait; Chisambi, Alvin; Witek-McManus, Stefan; Galagan, Sean R.; Emmanuel-Fabula, Mira; Gwayi-Chore, Marie-Claire; Legge, Hugo; Yard, Elodie; Kalua, Khumbo; Ibikounlé, Moudachirou; Ajjampur, Sitara Swarna Rao; Means, Arianna Rubin; Ásbjörnsdóttir, Kristjana; Halliday, Katherine E.; Walson, Judd L.

doi:10.1080/16549716.2020.1785146

Cited by 9 publications

(7 citation statements)

References 7 publications

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“…Additionally, it would still not ensure treatment of temporarily absent individuals, which was the most common recorded reason for non-treatment among adults in this analysis ( appendix p 2 ). The use of mobile health approaches, such as SMS monitoring, 26 District Health Information Software 2 27 and similar national systems, 28 or smartphone-based electronic treatment registers 29 to support data collection and decision making has been included in WHO guidelines. 30 Although such interventions need to be further assessed, 31 digital tracking approaches could improve targeting and treatment of urban and migrant populations, reduce costs, and increase coverage through real-time monitoring, and would in turn reduce systematic non-treatment.…”

Section: Discussionmentioning

confidence: 99%

Patterns of individual non-treatment during multiple rounds of mass drug administration for control of soil-transmitted helminths in the TUMIKIA trial, Kenya: a secondary longitudinal analysis

Oswald

Kepha

Halliday

et al. 2020

The Lancet Global Health

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Section: Discussionmentioning

confidence: 99%

Patterns of individual non-treatment during multiple rounds of mass drug administration for control of soil-transmitted helminths in the TUMIKIA trial, Kenya: a secondary longitudinal analysis

Oswald

Kepha

Halliday

et al. 2020

The Lancet Global Health

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“…In the India site, 115 trained field workers conducted a baseline household census between October and December 2017 across 219 villages in Timiri and 154 villages in Jawadhu Hills. At each PLOS NEGLECTED TROPICAL DISEASES household, following informed written consent provided by the household head or equivalent adult, household-and individual-level data were collected with a questionnaire programmed using SurveyCTO software (Dobility, Inc; Cambridge, MA and Ahmedabad, India) on an Android smartphone [34]. Demographic details such as age and sex were collected for all household members and were verified using state or central Government of India (GOI) issued identification cards (Aadhar card, Electoral Identity Card, Driving Licence or Birth Certificate).…”

Section: Baseline Censusmentioning

confidence: 99%

Epidemiology of soil transmitted helminths and risk analysis of hookworm infections in the community: Results from the DeWorm3 Trial in southern India

et al. 2021

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Since 2015, India has coordinated the largest school-based deworming program globally, targeting soil-transmitted helminths (STH) in ~250 million children aged 1 to 19 years twice yearly. Despite substantial progress in reduction of morbidity associated with STH, reinfection rates in endemic communities remain high. We conducted a community based parasitological survey in Tamil Nadu as part of the DeWorm3 Project—a cluster-randomised trial evaluating the feasibility of interrupting STH transmission at three geographically distinct sites in Africa and Asia—allowing the estimation of STH prevalence and analysis of associated factors. In India, following a comprehensive census, enumerating 140,932 individuals in 36,536 households along with geospatial mapping of households, an age-stratified sample of individuals was recruited into a longitudinal monitoring cohort (December 2017-February 2018) to be followed for five years. At enrolment, a total of 6089 consenting individuals across 40 study clusters provided a single adequate stool sample for analysis using the Kato-Katz method, as well as answering a questionnaire covering individual and household level factors. The unweighted STH prevalence was 17.0% (95% confidence interval [95%CI]: 16.0–17.9%), increasing to 21.4% when weighted by age and cluster size. Hookworm was the predominant species, with a weighted infection prevalence of 21.0%, the majority of which (92.9%) were light intensity infections. Factors associated with hookworm infection were modelled using mixed-effects multilevel logistic regression for presence of infection and mixed-effects negative binomial regression for intensity. The prevalence of both Ascaris lumbricoides and Trichuris trichiura infections were rare (<1%) and risk factors were therefore not assessed. Increasing age (multivariable odds ratio [mOR] 21.4, 95%CI: 12.3–37.2, p<0.001 for adult age-groups versus pre-school children) and higher vegetation were associated with an increased odds of hookworm infection, whereas recent deworming (mOR 0.3, 95%CI: 0.2–0.5, p<0.001) and belonging to households with higher socioeconomic status (mOR 0.3, 95%CI: 0.2–0.5, p<0.001) and higher education level of the household head (mOR 0.4, 95%CI: 0.3–0.6, p<0.001) were associated with lower odds of hookworm infection in the multilevel model. The same factors were associated with intensity of infection, with the use of improved sanitation facilities also correlated to lower infection intensities (multivariable infection intensity ratio [mIIR] 0.6, 95%CI: 0.4–0.9, p<0.016). Our findings suggest that a community-based approach is required to address the high hookworm burden in adults in this setting. Socioeconomic, education and sanitation improvements alongside mass drug administration would likely accelerate the drive to elimination in these communities. Trial Registration: NCT03014167.

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“…The questionnaire was administered by an interviewer in the local language using an android-based mobile platform (SurveyCTO; Dobility, Inc., Cambridge, MA, and Ahmedabad, India). 17 The survey was conducted in adherence to strict COVID-19 precautions.…”

Section: Methodsmentioning

confidence: 99%

Impact of the COVID-19 National Lockdown on a Rural and Tribal Population of Tamil Nadu, Southern India: A Mixed-Methods Survey

Ramesh

Aruldas

David

et al. 2022

The American Journal of Tropical Medicine and Hygiene

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We assessed the impact of the national lockdown on a rural and tribal population in Tamil Nadu, southern India. A mixed-methods approach with a pilot-tested, semi-structured questionnaire and focus group discussions were used. The impact of the lockdown on health, finances, and livelihood was studied using descriptive statistics. Multivariable logistic regression was carried out to identify factors associated with households that borrowed loans or sold assets during the lockdown, and unemployment during the lockdown. Of the 607 rural and tribal households surveyed, households from comparatively higher socioeconomic quintiles (adjusted odds ratio [aOR], 1.84; 95% CI, 1.01–3.34), with no financial savings (aOR, 2.91; 95% CI, 1.17–7.22), and with larger families (aOR, 1.76; 95% CI, 1.22–2.53), took loans or sold assets during the lockdown. Previously employed individuals from rural households (aOR, 5.07; 95% CI, 3.30–7.78), lower socioeconomic households (aOR, 3.08; 95% CI, 1.74, 5.45), and households with no savings (aOR, 1.78; 95% CI, 1.30–2.44) became predominantly unemployed during the lockdown. Existing government schemes for the elderly, differently abled, and widows were shown to be accessible to 89% of the individuals requiring these schemes in our survey. During the focus group discussions, the limited reach of online classes for schoolchildren was noted and attributed to the lack of smartphones and poor Internet connectivity. Although the sudden, unannounced national lockdown was imposed to flatten the COVID-19 curve, aspects related to livelihood and financial security were affected for both the rural and tribal populations.

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Development and application of an electronic treatment register: a system for enumerating populations and monitoring treatment during mass drug administration

Abstract: on behalf of the DeWorm3 Trials Team (2020) Development and application of an electronic treatment register: a system for enumerating populations and monitoring treatment during mass drug administration,

Cited by 9 publications

References 7 publications

Patterns of individual non-treatment during multiple rounds of mass drug administration for control of soil-transmitted helminths in the TUMIKIA trial, Kenya: a secondary longitudinal analysis

Patterns of individual non-treatment during multiple rounds of mass drug administration for control of soil-transmitted helminths in the TUMIKIA trial, Kenya: a secondary longitudinal analysis

Epidemiology of soil transmitted helminths and risk analysis of hookworm infections in the community: Results from the DeWorm3 Trial in southern India

Impact of the COVID-19 National Lockdown on a Rural and Tribal Population of Tamil Nadu, Southern India: A Mixed-Methods Survey

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