“…It is important to note the crucial task of choosing a suitable main biomaterial (e.g., metallic, polymeric, ceramic, or any combination) for the synthesis of high-performance feedstock materials with tuning parameters required for the 3D-printing process of bone-like structures [ 2 , 10 , 11 ]. In a sustainable manner, attention has shifted to biodegradable polymers, among which poly(lactic acid) (PLA) of natural origin (derived from maize, beet, or sugarcane) was nominated as an effective alternative with unique physico-chemical features (e.g., thermal stability, mechanical strength, and overall non-cytotoxicity) [ 7 , 12 , 13 , 14 ] and validated by the Food and Drug Administration (FDA) [ 15 , 16 ]. However, recent scientific advances have stipulated that the intrinsic brittleness and hydrophobic and inert surface features of PLA alone have to be mended properly for cells’ attachment and proliferation [ 6 , 15 , 17 , 18 ].…”