Developing role of magnetic resonance imaging in Crohn??s disease

Lin, Michael; Narra, Vamsidhar R.

doi:10.1097/mog.0b013e3282f49b14

Cited by 29 publications

(21 citation statements)

References 28 publications

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“…[7][8][9][10][11][12][13] Technical advances in MRI have yielded faster imaging with greater spatial resolution and image contrast. In humans, breath-holding, often in combination with peristalsis-suppressing drugs, allows the gut to be visualized in greater detail with far fewer motion artifacts.…”

mentioning

confidence: 99%

Progression and variability of TNBS colitis-associated inflammation in rats assessed by contrast-enhanced and T2-weighted MRI

Pohlmann

Tilling

Robinson

et al. 2009

Inflammatory Bowel Diseases

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confidence: 99%

Progression and variability of TNBS colitis-associated inflammation in rats assessed by contrast-enhanced and T2-weighted MRI

Pohlmann

Tilling

Robinson

et al. 2009

Inflammatory Bowel Diseases

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“…The selective application of ultrasound for assessing pediatric appendicitis is discussed below. There are a variety of scenarios where MRI can replace CT without loss of efficacy (25)(26)(27)(28)(29)(30)(31), common examples being imaging of the brain (26) and the lumbar spine (27). A recent study (29) suggested that about 27% of CT scans in young patients could, according to the European Community referral criteria (32), be replaced by MRI examinations.…”

Section: Replacing Ct Scans With Other Imaging Modalitiesmentioning

confidence: 99%

Slowing the Increase in the Population Dose Resulting from CT Scans

Brenner¹

2010

Radiation Research

118

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Brenner, D. J. Slowing the Increase in the Population Dose Resulting from CT Scans. Radiat. Res. 174, 809-815 (2010).The annual number of CT scans in the U.S. is now over 70 million. The concern is that organ doses from CT are typically far larger than those from conventional X-ray examinations, and there is epidemiological evidence of a small but significant increased cancer risk at typical CT doses. Because CT is a superb diagnostic tool and because individual CT risks are small, when a CT scan is clinically indicated, the CT benefit/risk balance is by far in the patient's favor. Nevertheless, CT should operate under the ALARA (As Low As Reasonably Achievable) principle, and opportunities exist to reduce the significant population dose associated with CT without compromising patient care. The first opportunity is to reduce the dose per scan, and improved technology has much potential here. The second opportunity is selective replacement of CT with other modalities, such as for many head and spinal examinations (with MRI), and for diagnosing appendicitis (selective use of ultrasound + CT). Finally, a fraction of CT scans could be avoided entirely, as indicated by CT decision rules: Clinical decision rules for CT use represent a powerful approach for slowing down the increase in CT use, because they have the potential to overcome some of the major factors that result in some CT scans being undertaken when they are potentially not clinically helpful. In the U.S. and potentially elsewhere, legislative approaches are a possible option, to improve quality control and reduce clinically unneeded CT use, and it is also possible that upcoming changes in heath care economics will tend to slow the increase in such CT use. g

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“…Oral contrast products are classified as positive, negative, and biphasic depending on how they influence the MRI scan: Positive contrast increases intraluminal signal, whereas the negative contrast reduces it. The MRE uses a biphasic contrast such as VoLumen (Bracco Diagnostics, Inc, Lake Success, NY) or Metamucil (Proctor & Gamble, Cincinnati, OH) (Lin & Narra, 2008). The amount of contrast will vary between radiologist and patient's age and weight.…”

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confidence: 99%

“…The nurse will then administer the first of two doses of glucagon as ordered by the radiologist. The adult dose of glucagon will be 1 mg subcutaneous/intramuscular/IV; the pediatric dose will be weight based (Lin & Narra, 2008). It is important for the nurse to be aware that glucagon must be mixed just before administration and can cause nausea in some patients.…”

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confidence: 99%