Abstract:Most antihypertensive drugs have impaired dissolution rate and result from poorly aqueous solubility, polymorphic modifications, structure-based H-bond donor or acceptor anamolies. These physical attributes would have detrimental effects and may cause an entity out of the race from efficacious candidates. Nevertheless, compliance with the dissolution rate must be fulfilled under the regulatory mandate and serve as an assessment tool for product performance. The present reviews the niche technologies like elect… Show more
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