Photonic artificial synapses-based neuromorphic computing systems have been regarded as promising candidates for replacing von Neumann-based computing systems due to the high bandwidth, ultrafast signal transmission, low energy consumption, and wireless communication. Although significant progress has been made in developing varied device structures for synaptic emulation, organic field-effect transistors (OFETs) hold the compelling advantages of facile preparation, liable integration, and versatile structures. As a powerful and effective platform for photonic synapses, OFETs can fulfill not only the simulation of simple synaptic functions, but also complex photoelectric dual modulation and simulation of the visual system. Herein, an overview of OFET-based photonic synapses, including functional materials, device configurations, and innovative applications is provided. Meanwhile, rules for selecting materials, mechanism of photoelectric conversion, and fabrication techniques of devices are also highlighted. Finally, challenges and opportunities are all discussed, providing solid guidance for multilevel memory, multi-functional tandem artificial neural system, and artificial intelligence.