This paper focuses on knowledge differences that occur between people and organizations, and various "dissimilar things," and presents the concept of "boundaries knowledge" or "boundaries knowing" that arises from the awareness, perception, and discovery by people and organizations of such differences. Then, through indepth case studies, the paper identifies the impacts that the quality of boundaries knowledge and boundaries knowing has on the creativity and innovation of people and organizations. Moreover, the paper shows that "boundaries knowledge (knowing)" is a strategic thinking and action that provides optimized creations, solutions, and processes for new knowledge creation such as strategy creation and execution as personal, organizational, or corporate targets, or solutions for problems and issues faced, as "the fourth knowledge" continuing from tacit knowledge, explicit knowledge, and phronesis.