Developing earthworm bioconcentration factors of nitrogen-based compounds for predicting environmentally significant parameters for new munition compounds in soil

Kuperman, Roman G.; Simini, Mike; Checkai, Ronald T.; Dodard, Sabine; Sarrazin, Manon; Hawari, Jalal; Paquet, Louise; Sunahara, Geoffrey I.; Toro, Dominic M. Di; Allen, Herbert E.; Kuo, Dave T.F.; Torralba–Sanchez, Tifany L.

doi:10.1016/j.apsoil.2015.11.008

Cited by 5 publications

(3 citation statements)

References 24 publications

(24 reference statements)

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“…Variable temperature may be necessary to reflect different field thermal conditions and varying optimal temperatures for individual invertebrates. The presence of solids/ substrates may be needed to support attachment (Agbo et al 2013), promote survival (Kuperman et al 2016), or prevent cannibalism (Weston et al 2009) in invertebrates. Re-examining some of these criteria for bioaccumulation data seems sensible and necessary for invertebrates that have been underinvestigated (e.g., midge).…”

Section: Introductionmentioning

confidence: 99%

A Reduced Model for Bioconcentration and Biotransformation of Neutral Organic Compounds in Midge

Kuo

Chen

2020

Enviro Toxic and Chemistry

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A bioconcentration factor (BCF) database and a toxicokinetic model considering only biota-water partitioning and biotransformation were constructed for neutral organic chemicals in midge. The database contained quality-reviewed BCF and toxicokinetic data with variability constrained to within 0.5 to 1 log unit. Diverse conditions in exposure duration, flow setup , substrate presence, temperature, and taxonomic classification did not translate into substantial variability in BCF, uptake rate constant (k 1), or depuration rate constant (k T), and no systematic bias was observed in BCFs derived in unlabeled versus radiolabeled studies. Substance-specific biotransformation rate constants k M were derived by difference between the calculated biota-water partitioning coefficient (K BW) and experimental BCF for developing a midge biotransformation model. Experimental midge BCF was modeled as BCF = K BW /(1 + k M/ k 2) with log k M (k M in h-1) =-0.37 log K OW-0.06T (in K) + 18.87 (root mean square error [RMSE] = 0.60), log k 1 (k 1 in L kg wet.wt-1 h-1) =-0.0747 W (body weight in mg wet.wt) + 2.35 (RMSE = 0.48). The K BW value was estimated using midge biochemical composition and established polyparameter linear free energy relationships, and the diffusive elimination rate constant (k 2) was computed as k 2 = k 1 /K BW. The BCF model predicted >85% of BCFs that associated with neutral organic compounds (log K OW = 1.46-7.75) to within 1 log-unit error margin and had comparable accuracy similar to amphipod or fish models. A number of outliers and critical limitations of the k M model were identified and examined, and they largely reflected the inherent limitation of difference-derived k M , the lack of chemical diversity, and inadequate temperature variation in existing data. Future modeling efforts can benefit from more BCF and toxicokinetic observations of BCF on structurally diverse chemicals for model training, validation, and diagnosis.

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Section: Introductionmentioning

confidence: 99%

A Reduced Model for Bioconcentration and Biotransformation of Neutral Organic Compounds in Midge

Kuo

Chen

2020

Enviro Toxic and Chemistry

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“…To assess the environmental risk of the co-pyrolyzed biochar, an earthworm (Eisenia fetida) acute toxicity test was conducted using aqueous exposure media. , In addition, to investigate the alleviation effect of soil [Fe 3+ ] on the toxicity of the NaCN-associated biochar, different concentrations of FeCl 3 solutions ranging from 0 to 40 mg/L were added during the test . Information on the selected biochar is listed in Table S1.…”

Section: Methodsmentioning

confidence: 99%

Toxicant Suppression in Co-pyrolysis of Chlorinated Paraffin-Containing Waste and N-Enriched Biomass

et al. 2022

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Pyrolysis is generally used to recycle and reuse plastic rubber and biomass waste. However, thermal cracking and recombination reactions of coexisting substances, such as chlorinated paraffins and protein, can induce toxic byproducts, including Cl-containing matter and alkali metal cyanides (MCN, e.g., NaCN and KCN). In this study, the simultaneous suppression of Cl volatilization and MCN formation was successfully achieved by the co-pyrolysis of two complementary wastes, including chlorinated paraffin-containing waste and N-enriched biomass. In the low-temperature co-pyrolysis reaction, the Cl atoms in the chlorinated paraffins were seized by the inherent alkali metals (Na or K) in the biomass to form NaCl or KCl in the biochar, leading to the suppression of Cl volatilization. This process simultaneously blocked the N atoms in the protein involved in the complexation reaction, thereby reducing the formation of NaOCN or KOCN (MCN precursor). In the high-temperature co-pyrolysis reaction, the reduction of NaOCN or KOCN and the physical barrier of NaCl or KCl adherence inhibited the formation of NaCN or KCN owing to the weakened carbothermal reduction. This proposed co-pyrolysis method represents a cost-effective technology that simultaneously suppresses Cl volatilization and MCN formation, reducing secondary pollution in the comprehensive utilization of solid wastes.

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“…The bioconcentration of PFAS in earthworms from water was performed by inducing four or five prepurged worms to 50 mL test solution in 250 mL test beakers containing glass beads (6 mm) as the solid component. 64 The test solution (pH: ∼7.4) was prepared with sterilized distilled water containing 1.0 × 10 −3 mol/L NaHCO 3 (buffer) and 1.0 × 10 −3 mol/L NaCl and spiked with a PFAS to a predetermined concentration (0.2 μmol/L). The test beakers were covered with a precleaned plastic wrap to prevent the escape of earthworms.…”

Section: ■ Introductionmentioning

confidence: 99%

In Vivo Generation of PFOA, PFOS, and Other Compounds from Cationic and Zwitterionic Per- and Polyfluoroalkyl Substances in a Terrestrial Invertebrate (Lumbricus terrestris)

Jin

Mallula

Golovko

et al. 2020

Environ. Sci. Technol.

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Perfluorooctanoate (PFOA) and perfluorooctanesulfonate (PFOS) are two environmentally persistent per- and polyfluoroalkyl substances (PFAS) that have been detected globally in human tissues and fluids. As part of a project investigating the indirect sources of PFOA/PFOS in the environment and engineered systems, this study is concerned with the mechanisms leading to their in vivo generation in terrestrial invertebrates. We demonstrate here the formation of PFOA and PFOS in earthworms (Lumbricus terrestris) from a group of four zwitterionic/cationic polyfluoroalkyl amides and sulfonamides. In bioaccumulation tests, the zwitterionic PFAS compounds were metabolized within 10 days to PFOA/PFOS at yields of 3.4–20.8 mol % by day 21 and several infrequently reported PFAS species for which chemical structures were determined using high-resolution mass spectrometry. Cationic PFAS, on the other hand, were found to be much less metabolizable in terms of the number (n = 2) and yields (0.9–5.1 mol %) of metabolites. Peak-shaped bioaccumulation profiles were frequently observed for the studied PFAS. Residual zwitterionic/cationic PFAS in earthworms were detected at the end of the elimination phase, indicating that not all zwitterionic/cationic PFAS molecules in vivo are available for enzymatic degradation. Finally, the relative importance of different exposure routes (i.e., waterborne and dietary exposure) was investigated.

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Developing earthworm bioconcentration factors of nitrogen-based compounds for predicting environmentally significant parameters for new munition compounds in soil

Cited by 5 publications

References 24 publications

A Reduced Model for Bioconcentration and Biotransformation of Neutral Organic Compounds in Midge

A Reduced Model for Bioconcentration and Biotransformation of Neutral Organic Compounds in Midge

Toxicant Suppression in Co-pyrolysis of Chlorinated Paraffin-Containing Waste and N-Enriched Biomass

In Vivo Generation of PFOA, PFOS, and Other Compounds from Cationic and Zwitterionic Per- and Polyfluoroalkyl Substances in a Terrestrial Invertebrate (Lumbricus terrestris)

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