Developing Classifications of Laryngeal Dysplasia: The Historical Basis

Hellquist, Henrik B.; Ferlito, Alfio; Mäkitie, Antti; Thompson, Lester D.�R.; Bishop, Justin A.; Agaimy, Abbas; Hernández-Prera, Juan C.; Gnepp, Douglas R.; Willems, Stefan M.; Slootweg, Pieter J.; Rinaldo, Alessandra

doi:10.1007/s12325-020-01348-4

Cited by 18 publications

(15 citation statements)

References 63 publications

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“…Grading of laryngeal dysplasia has moved to a binary system as described in detail in a recent review (Hellquist et al, 2020). Advantages of restricting diagnosis to high-and low-grade dysplasia in the larynx are suggested to be that it is easier for non-specialist pathologists to the prognostic value of the binary system slightly (Nankivell et al, 2013) but neither system convincingly prognosticated lesions in the moderate group any more accurately.…”

Section: B Inary G R Adingmentioning

confidence: 99%

Oral epithelial dysplasia: Recognition, grading and clinical significance

et al. 2021

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The concept of epithelial dysplasia was introduced into oral pathology over 60 years ago, following the recognition that some oral lesions had the potential to progress to oral cancer, now recognised as oral potentially malignant disorders (OPMDs). Attempts to grade oral dysplasia systematically were introduced into the literature in 1969, using photographic standards as reference (Smith et al., 1969) and internationally agreed classifications were formulated later

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Section: B Inary G R Adingmentioning

confidence: 99%

Oral epithelial dysplasia: Recognition, grading and clinical significance

et al. 2021

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“…[11][12][13][14] Correlations between pathologic classification and biologic behavior have been historically poor such that the World Health Organization recently simplified recommended pathologic categorization for vocal fold dysplasia. 15 Given the variations in care that patients may receive depending on the management approach that is recommended by the otolaryngologist, it is important for patients to have access to readable and understandable online materials to learn about available treatment options and participate in informed decision making. To our knowledge, no such readability analysis has been performed on patient education materials for vocal cord leukoplakia.…”

mentioning

confidence: 99%

“…Regarding vocal cord leukoplakia, there remain active discussions within the medical community on malignant potential and desired degree of surgical care (biopsy vs complete microflap removal), as well as the role of nonoperative management, use of angiolytic lasers, and potential for office‐based treatment 11–14 . Correlations between pathologic classification and biologic behavior have been historically poor such that the World Health Organization recently simplified recommended pathologic categorization for vocal fold dysplasia 15 . Given the variations in care that patients may receive depending on the management approach that is recommended by the otolaryngologist, it is important for patients to have access to readable and understandable online materials to learn about available treatment options and participate in informed decision making.…”

mentioning

confidence: 99%

Readability of Online Materials Related to Vocal Cord Leukoplakia

Shneyderman

Snow²,

Davis³

et al. 2021

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Objectives To assess readability and understandability of online materials for vocal cord leukoplakia. Study Design Review of online materials. Setting Academic medical center. Methods A Google search of “vocal cord leukoplakia” was performed, and the first 50 websites were considered for analysis. Readability was measured by the Flesch Reading Ease Score (FRES), Flesch-Kincaid Grade Level (FKGL), and Simple Measure of Gobbledygook (SMOG). Understandability and actionability were assessed by 2 independent reviewers with the PEMAT-P (Patient Education Materials Assessment Tool for Printable Materials). Unpaired t tests compared scores between sites aimed at physicians and those at patients, and a Cohen’s kappa was calculated to measure interrater reliability. Results Twenty-two websites (17 patient oriented, 5 physician oriented) met inclusion criteria. For the entire cohort, FRES, FKGL, and SMOG scores (mean ± SD) were 36.90 ± 20.65, 12.96 ± 3.28, and 15.65 ± 3.57, respectively, indicating that materials were difficult to read at a >12th-grade level. PEMAT-P understandability and actionability scores were 73.65% ± 7.05% and 13.63% ± 22.47%. Statistically, patient-oriented sites were more easily read than physician-oriented sites ( P < .02 for each of the FRES, FKGL, and SMOG comparisons); there were no differences in understandability or actionability scores between these categories of sites. Conclusion Online materials for vocal cord leukoplakia are written at a level more advanced than what is recommended for patient education materials. Awareness of the current ways that these online materials are failing our patients may lead to improved education materials in the future.

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“…The World Health Organization (WHO) histological classification system from 2005 31 in which mild dysplasia corresponds to LIN I, moderate dysplasia corresponds to LIN II and LIN III comprises severe dysplasia and carcinoma in situ. 32,33 Voice parameters were analyzed groupwise for LIN patients as posthoc analysis did not reveal any significant differences between subgroups (data not shown elsewhere).…”

Section: Patients and Inclusion Criteriamentioning

confidence: 99%