More than one in eight teenagers suffer from mental health issues like depression which is now becoming a common thing in society nowadays which can more often lead people to take extreme steps like suicides. Anti-Depression Chatbot is ideal, cost-effective, highly available web based Chatbot to help fight depression. Users can trust and turn to Anti-Depression Chatbot by simply using any browser for seeking help if they are feeling depressed. When user chats with Anti-Depression Chatbot about depression, mental health and things causing depression like toxic relationships, etc bot replies to user positively and provides information, advises user, etc in such a way that users depression level or sadness reduces. Anti-Depression Chatbot uses Natural Language Processing to understand user and replies with limited amount knowledge it has, to successfully reduce depression and boost mental health of user.