Developing a measure of medication-related quality of life for people with polypharmacy

Tseng, Hsu‐Min; Lee, Chia-Hui; Chen, Yin-Jen; Hsu, Hsiang-Hao; Huang, Li-Yueh; Huang, Jing‐Long

doi:10.1007/s11136-015-1177-2

Cited by 25 publications

(29 citation statements)

References 21 publications

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“…In the present study, we used the Medication-Related Quality of Life Scale version 1.0 (MRQoLS-v1.0) questionnaire, which is specific to patients with medication problems and has been recently validated as a measure of medication-related QoL (MRQoL) in patients with polypharmacy[15]. A better understanding of these medications related factors in older patients with polypharmacy may be useful to tailor interventions to the needs of individual patients in efforts to improve overall care and HRQoL.…”

Section: Introductionmentioning

confidence: 99%

Medication-related quality of life among Ethiopian elderly patients with polypharmacy: A cross-sectional study in an Ethiopia university hospital

et al. 2019

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Polypharmacy among older patients has been associated with a decline in their quality of life. We aimed to assess the medication-related quality of life (MRQOL) among older patients with polypharmacy at Gondar University Hospital, Gondar, Ethiopia. A prospective cross-sectional study was carried out among 150 elder patients who had visited the internal medicine ward and ambulatory ward of Gondar referral hospital from March 25 to May 15, 2017, using a validated scale, Medication-Related Quality of Life Scale version 1.0 (MRQoLS-v1.0). A total of 150 older patients with polypharmacy participated in the study with a mean age of 70.06±5.12, andtwo-thirds of the participants (67.3%) were female. The overall prevalence of poor quality of life due to polypharmacy in the current study was found to be three fourth (75.3%) of the participants. Regarding the severity of impairment in MRQoL, Univariate analysis revealed that frequency of hospital visits (COR = 1.34, 95% CI, 1.02–1.77) and medication number (COR = 1.94, 95% CI, 1.33, 2.8) had a statistically significant positive association with the likelihood of having a severe impairment.The multivariate analysis also showed that one unit increase in the number of hospital visits (AOR = 1.45, 95% CI, 1.040–2.024) and medications greater than 5 (AOR = 1.91, 95% CI, 1.29, 2.84) increases 1.45 and 1.91 times the likely hood of posing severe impairment of MRQoL, respectively. As far as poor MRQoL quality of life is concerned, multivariate analysis did not show any significant association between the poor MRQoL;and Sociodemographic and clinical data of patients. The poor QoL associated with medication was very high in this study. Deprescribing should be sought by the health care providers to optimize drug therapy and minimize the polypharmacy related poor quality of life.

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Section: Introductionmentioning

confidence: 99%

Medication-related quality of life among Ethiopian elderly patients with polypharmacy: A cross-sectional study in an Ethiopia university hospital

et al. 2019

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“…A further instrument, developed in Taiwan and published since the literature review was completed, claims to measure Medication-Related Quality of Life, 76 a term originally adopted for the LMQ. 77 This instrument was developed based on subjective well-being scales plus patient interviews and consists of 14 items, covering only three domains: role limitations, self-control, and vitality.…”

Section: Discussionmentioning

confidence: 99%

“…77 This instrument was developed based on subjective well-being scales plus patient interviews and consists of 14 items, covering only three domains: role limitations, self-control, and vitality. 76 Only the first of these relates directly to medicines burden, as discussed in this review; therefore, this instrument too is limited.…”

Section: Discussionmentioning

confidence: 99%

Measuring medicine-related experiences from the patient perspective: a systematic review

Katusiime¹,

Corlett²,

Reeve³

et al. 2016

PROM

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BackgroundThere is an increasing drive to measure and so improve patients’ experiences and outcomes of health care. This also applies to medicines, given their ubiquity as health care interventions. Patients’ experiences of using medicines vary, and instruments which measure these are seen as an essential component to improve care. We aimed to identify generic measures of patients’ experiences of using prescription medicines and to examine their properties and suitability for use in research or practice.MethodsMultiple electronic databases were searched: MEDLINE, Embase, PsycINFO, PsycARTICLES, CINHAL Plus, PROQOLID®, and Google Scholar. We identified, critically appraised, and summarized generic questionnaires assessing one or more aspects of the medicine use experience among adult patients using prescription medicines for chronic conditions, and the process of questionnaire development, degree of patient involvement, and/or validation processes.ResultsFifteen questionnaires were included. Of these, nine measures were multidimensional, covering various aspects of medicine use. Six instruments covered only a single domain, assessing a specific facet of using medicines. Domains covered were the following: effectiveness; convenience, practicalities, and/or managing medicines; information, knowledge, and/or understanding; side effects; relationships and/or communication with health professionals; impact on daily living and/or social life; general satisfaction; attitudes; beliefs, concerns, and/or perceptions; medical follow-up and/or adherence-related issues; treatment- and/or medicine-related burden, perceived control, or autonomy; self-confidence about medicine use; availability and accessibility; and medicine-related quality of life. None of the identified questionnaires covered all domains. Instruments varied in the extent of patient involvement in both their development and validation.ConclusionThere is a scarcity of psychometrically sound, comprehensive, and generic measures of experiences of using prescription medicines among adult patients living with chronic illnesses. There is a need for further development and/or validation of existing instruments suitable for use in this population.

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“…Keijsers and others showed that the walking speed of a healthy subject on a force plate can be predicted by the subject's plantar pressure center, and the average pressure center speed predicts that the healthy subject will be 95% of his preferred walking speed [51]. Accuracy, precision can reach 0.2m / s. Although weightbearing magnetic resonance diagnosis has the characteristics of directly displaying lesions, its value as a conventional diagnostic tool has been questioned because of its traumatic nature [52].…”

Section: Introductionmentioning

confidence: 99%

Analysis of Clinical Value of Weight-Bearing Magnetic Resonance Diagnosis of Ankle Ligament Sports Injury

Hong-mei

Feng²

2020

IEEE Access

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Observe and analyze the effect of weighted magnetic resonance imaging in the diagnosis of ankle ligament sports injury. Methods: A total of 50 patients with ankle ligament sports injuries were recruited as research subjects to conduct clinical diagnostic research. After admission, the patient first underwent MRI diagnosis of ankle joint ligament sports injury and then received surgical treatment. Based on the results of surgical treatment, the diagnostic effect of weighted magnetic resonance imaging and the detection of concurrent injuries were compared. After surgery, a total of 24 cases of ankle ligament contusion were confirmed in 50 patients, 19 cases were partially ruptured, 7 cases were completely ruptured, and 26 cases had joint effusion, tendon injuries in 17 cases, fractures in 8 cases, and talar articular cartilage lesions in 19 cases. After comparison, there was no significant difference between the results of weight-bearing magnetic resonance diagnosis and the detection rate of concurrent injuries compared with the surgical results, P> 0.05. Conclusion: The application of weight-bearing magnetic resonance imaging in the diagnosis of ankle ligament sports injury can effectively diagnose the patient's ligament injury and the type of combined injury, and has significant clinical application value.

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Developing a measure of medication-related quality of life for people with polypharmacy

Cited by 25 publications

References 21 publications

Medication-related quality of life among Ethiopian elderly patients with polypharmacy: A cross-sectional study in an Ethiopia university hospital

Medication-related quality of life among Ethiopian elderly patients with polypharmacy: A cross-sectional study in an Ethiopia university hospital

Measuring medicine-related experiences from the patient perspective: a systematic review

Analysis of Clinical Value of Weight-Bearing Magnetic Resonance Diagnosis of Ankle Ligament Sports Injury

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