Developing a cancer‐specific geriatric assessment

Abstract

Talon cusps are rare morphological features of the anterior dentition that represent a spectrum of lingual cingulum diversity. In this paper, talon cusp prevalence is described in two Archaic period North American samples, Windover Pond (Florida) and Buckeye Knoll (Texas). Given the early date of these cemeteries (∼7500 BP), these specimens represent the oldest reported cases of lingual talon cusp in the New World, and perhaps globally. Windover preserves three cases of talon cusp (representing three different individuals) affecting the permanent maxillary lateral incisors. The sample frequencies were 1.8% and 3.1% for the left and right maxillary lateral incisors, respectively. Buckeye Knoll preserves four cases of talon cusp representing three individuals. Talon cusps at this site were distributed throughout the maxillary anterior dentition, including a permanent maxillary central incisor, bilateral permanent maxillary lateral incisors, and a deciduous maxillary lateral incisor. The multicomponent nature of this site complicates sample frequency calculation with by‐tooth estimates ranging from 3.6% to 25%. This paper discusses the difficulties with comparative frequency estimation, resulting from a proliferation of terminology that is discipline‐specific. Understanding the evolutionary basis and significance of dental morphological variation requires an inclusive approach to the comparative literature that focuses on homology within the context of odontogenetic process. Am J Phys Anthropol, 2011. © 2010 Wiley‐Liss, Inc.

Perspectives and Attitudes on the Use of Adjuvant Chemotherapy and Trastuzumab in Older Adults with HER-2+ Breast Cancer: A Survey of Oncologists

“…In addition, because an increasing proportion of respondents recommended trastuzumab monotherapy as patient age increased or health status worsened, further studies regarding the efficacy and toxicity of single-agent trastuzumab in the adjuvant setting are needed. Given the lack of uniformity of therapeutic recommendations based on age and health status, recently developed metrics to assess factors other than chronological age that predict morbidity and mortality in an older patient population may be useful in these proposed efforts [15,16]. Additionally, the use of endpoints such as quality of life, in addition to disease-free and overall survival times, may lead to more meaningful clinical outcomes.…”

Perfil clínico-epidemiológico de idosos submetidos à quimioterapia antineoplásica atendidos em um hospital de referência oncológica do estado do Pará, Brasil

“…Entretanto, como alternativa para minimizar riscos e direcionar os profissionais da área da saúde, quanto ao tratamento e ao plano de cuidados mais adequados, diversos autores sugerem a utilização de uma avaliação geriátrica abrangente, para que sejam preenchidas lacunas de conhecimento 34,35,36 . A avaliação geriátrica abrangente é definida como um processo de diagnóstico multidimensional e interdisciplinar com foco na determinação das capacidades clínicas, psicossociais e funcionais de idosos, a fim de se desenvolver um plano coordenado e integrado de tratamento seguido a longo prazo.…”

Evaluating the Older Patient with Cancer: Understanding Frailty and the Geriatric Assessment

“…The self-administered format of the geriatric assessment appeared to be feasible, with patients completing the questionnaire within an average of 15 minutes. The Cancer and Leukemia Group B (CALGB) is leading an effort to evaluate the feasibility of incorporating a primarily self-administered geriatric assessment 94 into its ongoing protocols (CALGB 360401). 95 Efforts such as these may ultimately aid in prospectively validating the stratification of treatment by geriatric assessment result.…”