Develop and Validate a Stability-Indicating HPLC Assay Method for Paracetamol, and parabens in Pharmaceutical Dosages
Mahfoudh Al-Hamadi,
Abdualqawi A. Numan,
Amjd Hadi Alshmmakh
et al.
Abstract:The drug's stability, which is a prerequisite for good drug quality, cannot be simply established unless a reliable and trustworthy method for demonstrating stability is applied. Creating such a method is a challenging task. In this work, we developed and validated a reversed-phase stability indicating liquid chromatographic technique with photo diode-array detection to analyze paracetamol (PCM), methylparaben (MP), propylparaben (PP), and their degradants in commercial oral suspension. The compounds and th… Show more
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