Devastating Consequences of a Jailed Knuckled Wire in CTO PCI of an Anomalous RCA

Karagöz, Ahmet; Kılıç, Derya; Göktekín, Ömer

doi:10.1016/j.jaccas.2019.11.082

Cited by 3 publications

(2 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This method has the advantages of high sensitivity, high specificity, low contamination, and stable reaction. Possible reasons for this are, on the one hand, the low efficiency of SAT assay using the traditional boiling lysis method for nucleic acid extraction, coupled with the high number of inhibitors of SAT assay reactions in the urine composition, resulting in the insensitivity of SAT assay to urine and affecting nucleic acid ampli-fication [25]. In contrast, the isolated culture method, which is the gold standard for the diagnosis of gonorrhea pathogenic bacteria, has high requirements for the environment, collection, and transport of specimens and also may lead to missed detection due to antibiotic use and inactivation of pathogenic microorganisms after inoculation [26].…”

Section: Discussionmentioning

confidence: 99%

Application of Isothermal Signal Amplification Technique in the Etiological Diagnosis of Gonorrhea and Drug Resistance Gene Detection

Chen

Zhang

et al. 2022

Computational and Mathematical Methods in Medicine

View full text Add to dashboard Cite

Background: Isothermal signal amplification technique is developed based on the rolling ring amplification mechanism of cyclic DNA molecules in nature. This technique plays an extremely beneficial role in gonorrhea pathogen identification and drug resistance gene detection. Aims: This study analyzes the isothermal signal amplification techniques in the etiological diagnosis of gonorrhea and drug resistance gene detection. Materials and Methods: Urethral, cervical secretion, or prostatic fluid samples from 322 cases of gonorrhea collected from January 2018 to December 2021 at the STD clinic of our hospital dermatology department were selected for direct smear examination and gonococcal culture examination; DNA was extracted from urethral, cervical secretion, or prostatic fluid samples and then used for pathogen identification by SAT assay and rolling loop nucleic acid amplification technique, smear examination and pathogen culture examination methods, SAT assay, and isothermal signal amplification technique for comparative sensitivity and specificity analysis. Results: The highest rate of gonorrhea positivity was for the urine rolling loop nucleic acid amplification technique, followed by the swab rolling loop nucleic acid amplification technique, and the lowest rate of gonorrhea positivity was for the urine SAT test. The difference in the positivity rate between the two urine testing methods was statistically significant ( P < 0.05 ). The highest sensitivity of the urine rolling loop nucleic acid amplification technique method for the detection of gonorrhea pathogens and the lowest sensitivity of the urine SAT method were statistically significant ( P < 0.01 ). The differences in sensitivity and specificity between the swab rolling loop nucleic acid amplification technique and the swab SAT method were not statistically significant ( P > 0.05 ). ROC curves were plotted based on sensitivity and specificity, with swab SAT assay ( A U C = 0.998 ) > rolling loop nucleic acid amplification technique ( A U C = 0.981 ). Comparing the negative rates of urine and swab rolling loop nucleic acid amplification technique and urine SAT assay, the differences were not statistically significant ( P > 0.05 ). Conclusion: The isothermal signal amplification technique improves the shortcomings of gonorrhea pathogen identification means and drug resistance gene detection methods, with good detection sensitivity and specificity, simple operation, low price, and easy promotion, which has obvious advantages in clinical applications and epidemiological studies.

show abstract

Section: Discussionmentioning

confidence: 99%

Application of Isothermal Signal Amplification Technique in the Etiological Diagnosis of Gonorrhea and Drug Resistance Gene Detection

Chen

Zhang

et al. 2022

Computational and Mathematical Methods in Medicine

View full text Add to dashboard Cite

show abstract

“…We had successful PCI in 4 out of 5 CTO cases, 2 of which even required a rotablation for the balloon-uncrossable, calcified CTO lesion. Though transfemoral access is the preferred route for PCI 3,4,6,7,9 , transradial access was also attempted by Lin et al 6…”

Section: Discussionmentioning

confidence: 99%

Percutaneous coronary intervention of anomalous right coronary arteries arising from the left sinus of Valsalva: a single-centre experience from Northern India

Vijayvergiya¹,

Gupta²,

Kasinadhuni³

et al. 2023

AsiaIntervention

View full text Add to dashboard Cite

Background: An anomalous right coronary artery (ARCA) arising from the left sinus of Valsalva is an uncommon congenital anomaly. The unusual location, take-off and intramural courses of ARCA pose a considerable technical challenge during percutaneous coronary intervention (PCI). Aims:We sought to report our experience of PCI of ARCA in 35 cases of atherosclerotic occlusion. Methods: The PCI database of 35 cases of ARCA was retrospectively analysed. The details about demography, clinical presentation, PCI procedure and clinical follow-up were noted. Results:The mean age was 56.7±13.5 years. The clinical presentation included stable angina in 45.7%, unstable angina in 20% and acute myocardial infarction in 34.3% of patients. Vascular access was transradial in 37.1% of cases, transfemoral in 60% of cases, and transbrachial in 1 case (2.9%). Judkins left and Amplatz left were commonly used guide catheters. Two patients with balloon-uncrossable, calcified lesions required rotablation-assisted PCI. Intravascular imaging was performed in 12 patients (34.3%). Optical coherence tomography demonstrated a proximal intramural course in 3 patients, and a slit-like orifice in 4 patients. The mean radiation dose and fluoroscopy time were 877±687.3 mGy and 18.8±11.6 minutes, respectively. Twenty-eight (80%) patients had an asymptomatic median follow-up of 49 (interquartile range: 29.0-97.5) months. Conclusions:We performed successful PCI in a cohort of 35 patients with ARCA, with favourable longterm clinical outcomes. The selection of an appropriate guide catheter and technical skills were important factors in achieving favourable results.

show abstract

Bifurcations and CTOs

Brilakis¹

2023

Manual of Chronic Total Occlusion Percutaneous Coronary Interventions

View full text Add to dashboard Cite

Devastating Consequences of a Jailed Knuckled Wire in CTO PCI of an Anomalous RCA

Abstract: A knuckled tip of a jailed guidewire may lead to distortion of the main branch stent when pulled back after balloon dilatation of the side branch ostium. The distorted stent can be crushed to the side of the vessel as a bail-out intervention. ( Level of Difficulty: Advanced. )

Cited by 3 publications

References 5 publications

Application of Isothermal Signal Amplification Technique in the Etiological Diagnosis of Gonorrhea and Drug Resistance Gene Detection

Application of Isothermal Signal Amplification Technique in the Etiological Diagnosis of Gonorrhea and Drug Resistance Gene Detection

Percutaneous coronary intervention of anomalous right coronary arteries arising from the left sinus of Valsalva: a single-centre experience from Northern India

Bifurcations and CTOs

Contact Info

Product

Resources

About