Detoxication Mechanisms and the Role of Nutrition

Gibson, Gordon

doi:10.1007/978-1-4899-2447-6_9

Cited by 2 publications

(1 citation statement)

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“…Methylmercury is highly toxic to the central nervous system (Gibson, 1992;Gochfeld, 2008;OEHHA, 2004;Osterloh and Tarcher, 1992;Palmer and Bakshi, 1992;Taylor, 1992). In the past century, incidents of mercury intoxication related to food occurred in Japan (Minamata, Niigata, Tokuyama), China (Guizhou), the Faroe Islands, Seychelles Republic, Canada (Ontario), New Zealand, and Iraq.…”

Section: Introductionmentioning

confidence: 99%

Determining mercury levels in anchovy and in individuals with different fish consumption habits, together with their neurological effects

et al. 2014

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An increase in enviromental pollution may lead to mercury toxicity of fish origin due to the accumulative nature of methylmercury in fish. The main sources of human exposure to organic mercury compounds are contaminated fish and other seafoods. This descriptive study was planned to determine mercury levels in anchovy and in hair samples from individuals with different fish consumption habits, and to evaluate those individuals in terms of toxic effects. For that purpose, we analyzed 100 anchovies from the Black Sea and 100 anchovies from the Sea of Marmara, and assessed 25 wholesale workers in fish markets and 25 cleaning firm employees from both Ankara and Istanbul. Mercury levels in samples were measured using a cold vapor atomic absorption spectrophotometer. Participants were examined neurologically and mini mental state examination was applied to evaluate their cognitive functions. Mercury levels in fish were found to be below the national and international permitted levels. There was no statistically significant relation between mercury levels and the sea from which fish were caught. Hair mercury levels for all participants were within permitted ranges. However, hair mercury levels in both cities increased significantly with amount and frequency of fish consumption. A significant correlation was determined at correlation analysis between levels of fish consumption and hair mercury levels in the fishmongers and in the entire group (r = 0.32, p = 0.025; r = 0.23, p = 0.023, respectively). Neurological examination results were normal, except for a decrease in deep tendon reflexes in some participants in both cities. There was no correlation between Standardized Mini Mental State Examination results and hair mercury levels. We conclude that establishing a monitoring system for mercury levels in fish and humans will be useful in terms of evaluating potential neurotoxic effects.

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Section: Introductionmentioning

confidence: 99%

Determining mercury levels in anchovy and in individuals with different fish consumption habits, together with their neurological effects

et al. 2014

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Natural Phytotherapeutic Antioxidants in the Treatment of Mercury Intoxication-A Review

Ünsal¹

2018

Adv Pharm Bull

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Heavy metals taken into the organism can make the toxic effects on the metabolism in various ways. For example, they may interact with proteins to alter and inhibit their enzymatic and structural functions. Mercury is one of the toxic elements that are widely distributed in nature. Mercury toxicity poses a serious threat to human health. It is an element that causes oxidative stress to increase in individuals, leading to tissue damage. Oxidative stress is the result of the imbalance between the production of oxidative species and cellular antioxidant defense. Phytotherapy continues to play an important role in health care. Natural phytotherapeutic antioxidants, exhibit a broad sequence of biological impacts, including anti-oxidative stress, anti-aging, anti-toxicicity and anticancer. Many studies have also shown that the phytotherapeutic agents play an important role in the removal of mercury from the tissue and in reducing oxidative stress. Our goal in this review was to investigate alternative ways of extracting the mercury in the tissue.

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Detoxication Mechanisms and the Role of Nutrition

Cited by 2 publications

References 101 publications

Determining mercury levels in anchovy and in individuals with different fish consumption habits, together with their neurological effects

Determining mercury levels in anchovy and in individuals with different fish consumption habits, together with their neurological effects

Natural Phytotherapeutic Antioxidants in the Treatment of Mercury Intoxication-A Review

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