Deterministic and Stochastic Trajectories of Magnetic Particles: Mapping Energy Landscapes for Technology And Biology

Howdyshell, M.; Prikockis, M.; Lauback, S.; Vieira, G.; Mahajan, Kalpesh; Winter, Jessica O.; Sooryakumar, R.

doi:10.1109/tmag.2014.2323959

Cited by 3 publications

(3 citation statements)

References 27 publications

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“…Although every magnetic material may exhibit a magnetocaloric effect, which has many advantages, such as large surface area, good biocompatibility, superparamagnetic properties and easy controllability via external magnetic field conditions. 85 Even though every magnetic material may exhibit a magnetocaloric effect, superparamagnetic nanoparticles are still the most promising nanomaterials for magnetic hyperthermia treatment. The concept of superparamagnetism refers to the phenomenon that a single domain can be formed to induce strong magnetization of magnetic materials at a certain small size.…”

Section: Magnetic Hyperthermia Therapy (Mht)mentioning

confidence: 99%

Functional anti-bone tumor biomaterial scaffold: construction and application

et al. 2023

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Section: Magnetic Hyperthermia Therapy (Mht)mentioning

confidence: 99%

Functional anti-bone tumor biomaterial scaffold: construction and application

et al. 2023

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“…A slightly different approach relies on the motion of DWs constrained in thin ferromagnetic conduits. 94,95 These magnetic elements have been fabricated from Fe 0.5 Co 0.5 (M s ∼ 2 T), 47,59,[96][97][98][99][100] Ni, 101 or NiFe, [102][103][104][105][106][107][108][109][110][111] in shapes that included zigzag wires, 47,59,96,97,100,102-106 rings, 101,103,104,107-109 squares, 104 straight wires with periodic indentations, 98 and curvilinear tracks. 110 Examples of conduits patterned on polymeric 105 or piezoelectric substrates, 101 have also been reported.…”

Section: Domain Wall (Dw) Motion In Thin Magnetic Films and Conduitsmentioning

confidence: 99%

Micromagnet arrays enable precise manipulation of individual biological analyte–superparamagnetic bead complexes for separation and sensing

Rampini

2016

Lab Chip

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In this article, we review lab on a chip (LOC) devices that have been developed for processing magnetically labelled biological analytes, e.g., proteins, nucleic acids, viruses and cells, based on micromagnetic structures and a time-varying magnetic field. We describe the methods that have been developed for fabricating micromagnetic arrays and the bioprocessing operations that have been demonstrated using superparamagnetic (SPM) beads, i.e., programmed transport, switching, separation of specific analytes, and pumping and mixing of fluids in microchannels. The primary advantage of micromagnet devices is that they make it possible to develop systems that control individual SPM beads, enabling high-efficiency separation and analysis. These devices do not require hydrodynamic control and lend themselves to parallel processing of large arrays of SPM beads with modest levels of power consumption. Micromagnet devices are well suited for bioanalytical applications that require high-resolution separation, e.g., detection of rare cell types such as circulating tumour cells, or biosensor applications that require multiple magnetic bioprocessing operations on a single chip.

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“…Magnetic nanoparticles have many advantages, such as small size, large surface area, low toxicity, biocompatibility, and superparamagnetic properties [19]. Additionally, the motion trajectory of magnetic nanoparticles can be controlled via external magnetic field conditions [20,21]. Therefore, there have been many studies reported in the literatures concerning the immobilization or adsorption of enzymes with ferrite nanoparticle-polymer composites [22,23].…”

Section: Introductionmentioning

confidence: 99%

Lysozyme Aptamer-Functionalized Magnetic Nanoparticles for the Purification of Lysozyme from Chicken Egg White

Luo

Zhou

Chen

et al. 2019

Foods

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Lysozyme is in high demand due to its many favorable characteristics such as being naturally occurring, non-toxic, and easy to digest and absorb. Recently, superparamagnetic nanoparticles with strong magnetic responsiveness have attracted significant interest for enzyme purification. The aptamer of the enzyme can be chemically synthesized rapidly at a large scale using simple and low-cost preparation methods. Therefore, Fe3O4 nanoparticles (Fe3O4 NPs) were prepared by chemical co-precipitation and were then functionalized with amino groups to produce NH2-Fe3O4 NPs. The specific reaction of aldehyde and amino groups was used to attach lysozyme aptamers with specific sequences to NH2-Fe3O4 NPs to produce Apt-NH2-Fe3O4 NPs. The synthesized materials were characterized using transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), hysteresis loop analysis, and thermogravimetric analysis (TGA). The optimal experimental conditions for adsorption of lysozyme were investigated. The effects of initial lysozyme concentration, adsorption time, pH, reaction temperature, and ionic strength were determined. The maximum adsorption capacity and relevant activity of Apt-NH2-Fe3O4 NPs was 460 mg·g−1 and 16,412 ± 55 U·mg−1 in an aqueous lysozyme solution. In addition, as demonstrated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) electrophoresis analysis, lysozyme could be separated from crude fresh egg white using Apt-NH2-Fe3O4 NPs with an amount up to 113 ± 4.2 mg·g−1 and an activity up to 16,370 46 U·mg−1.

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Deterministic and Stochastic Trajectories of Magnetic Particles: Mapping Energy Landscapes for Technology And Biology

Cited by 3 publications

References 27 publications

Functional anti-bone tumor biomaterial scaffold: construction and application

Functional anti-bone tumor biomaterial scaffold: construction and application

Micromagnet arrays enable precise manipulation of individual biological analyte–superparamagnetic bead complexes for separation and sensing

Lysozyme Aptamer-Functionalized Magnetic Nanoparticles for the Purification of Lysozyme from Chicken Egg White

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