Determining the Risks of Magnetic Resonance Imaging at 1.5 Tesla for Patients With Pacemakers and Implantable Cardioverter Defibrillators: The Magnasafe Registry

Preclinical evaluation of implantable cardioverter-defibrillator developed for magnetic resonance imaging use

“…20 A multicenter registry was recently completed, assessing the risk of MRI in device patients undergoing a medically necessary nonthoracic scan. 22 Although adverse events are low in these reports, these studies have several limitations. First, the sample size of ICDs is limited because many of the studies included both pacemakers and ICDs.…”

“…In addition, the 2 largest studies excluded pacemaker-dependent ICD patients. 20,22 A wide variety of CIED system components, imaging techniques, and patient positions are used within each study, which decreases the statistical power to assess the safety of any of these combinations. Finally, the relationship between the strength of MR fields and adverse responses are not quantified, so the limits of safe scanning cannot be defined accurately.…”

Comprehensive review on cardio-oncology: Role of multimodality imaging

“…79 A subsequent multicenter prospective study, the MagnaSafe Registry, to determine the risks of nonthoracic 1.5 Tesla MRI scan in patients with implanted pacemakers and Implantable CardioverterDefibrillators (ICDs), reported no device failure, generator/lead replacement, induced arrhythmia, or loss of capture in the first 829 cases 80 , nor in the first 1189 cases. 81 A study of 68 MRI scans in pacemaker patients (with MR-conditional vs. MR-unsafe pacing systems) documented clinical safety of MRI in both groups, with no significant differences between those undergoing thoracic MRI compared to other scanned areas. 82 The subsequent availability of MRI-safe implantable cardiac devices has facilitated the utilization of MRI (including CMRi) in the clinical setting.…”

Full-Body MRI in Patients With an Implantable Cardioverter-Defibrillator

“…Specifically, several single-center trials have shown that such imaging can be performed safely in certain situations (17,18). Although adverse events are low in these reports, these studies typically restricted scans to nonthoracic regions, excluded pacemaker-dependent patients, and included a small proportion of ICD patients compared with pacemaker patients (19). By including a wide variety of cardiovascular implantable electronic device system components, imaging techniques, and patient positions in these studies, an evaluation of safety is difficult to assess.…”