Determining hemoglobin reference values in children and teenagers from Sibiu area

Totali, Mana; Gligor, Felicia Gabriela; Bojiţă, Marius; Grigore, Camelia Ana; Grigore, Cristina

doi:10.2478/rrlm-2013-0016

Cited by 8 publications

(7 citation statements)

References 5 publications

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“…This is the main reason which caused alternative methods to be found and indirect methodologies to be encouraged by IFCC Committee on Reference Intervals and Decision Limits (8). Starting 2013, the Romanian Journal of Laboratory Medicine has published several articles proposing Hoffmann technique (9, 10) for determinations of reference intervals for hemoglobin, serum total magnesium and calcium in Romanian children (11,12), and decision limits for serum uric acid associated with cardiovascular morbidity and metabolic syndrome in this issue (13). On the other hand, by using the reference ranges concept for interpretation of test results there is a grey area where superposition of values from healthy and ill subject exists.…”

Section: Scope Of Laboratory Medicine In the Era Of Precision Medicinmentioning

confidence: 99%

Laboratory medicine in the era of precision medicine – dream or reality?

Dobreanu

Oprea

2019

Revista Romana De Medicina De Laborator

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Section: Scope Of Laboratory Medicine In the Era Of Precision Medicinmentioning

confidence: 99%

Laboratory medicine in the era of precision medicine – dream or reality?

Dobreanu

Oprea

2019

Revista Romana De Medicina De Laborator

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“…The mechanism includes gene replacements, gene blockade and gene modification. Target for gene therapy are genes such as p21CIP1/WAF1, BCRP, K-ras, p14ARF, p16INK4A/CDKN2A, LSM1/ CaSm, VEGF, HER-2/EerB-2, and MDR1 [44][45][46][47][48][49]. New therapies are urgently needed because conventional treatments, like radiotherapy and chemotherapy, are useful in a small number of patients with PC.…”

Section: Pancreasmentioning

confidence: 99%

Retroperitoneal Tumours - Treatment and Prognosis of Tumour Recurrence

Bratu¹,

Cherciu²,

Bumbu³

et al. 2019

Rev. Chim.

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Retroperitoneal tumors, once considered uncommon, have been reported in the last years in such numbers that they cannot be considered anymore a rare condition. Tumor recurrence following surgical excision is quite common and a tumor that was considered originally as benign in many cases can recur as a malignant tumor. The purpose of this paper is to underline the difficulties in terms of establishing a correct diagnosis and a proper therapeutic protocol when facing a retroperitoneal mass of unknown origin, as well as to present the available data regarding prognosis, treatment options and tumor recurrence. Retroperitoneal tumors can be classified as benign or malignant; solid, cystic or both; single or multiple, and of varied histological types. A high percentage of patients with retroperitoneal tumors are discovered in advanced stages, usually seeking medical help for symptoms related to nearby organ compression/invasion. This pathology requires a prompt and adequate multidisciplinary management, in order to achieve disease control and to reduce the recurrence rate. Complete surgical resection is the potential curative treatment for retroperitoneal tumors and it is best managed in high-volume centers, by a multidisciplinary team. Complete oncological tumor resection and tumor grade remain the most important predictors for local recurrence and disease-specific survival. Further research is required in order to define the role of radiotherapy, as well as to discover new biological therapies that target various molecular pathways involved in retroperitoneal cancers.

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“…It can also be used to perform CT-guided biopsies to confirm the diagnosis of sarcoma. Image-guided biopsies are strongly recommended, unless the image is pathognomonic and no preoperative treatment is planned [20][21][22][23]. When the tumor does not contain fat, sarcoma is the correct final diagnosis in more than 50% of cases, but the rest of the patients may need a different therapeutic protocol.…”

mentioning

confidence: 99%

Vascular Involvement in Primary Retroperitoneal Tumors

Marcu¹,

Ioniţă-Radu²,

Iorga³

et al. 2019

Rev. Chim.

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The retroperitoneum can host a wide variety of pathologies, including benign and malignant tumors. Primary retroperitoneal tumors are rare, usually large in size, more than half of them being larger than 20 cm at the time of diagnosis, due to their silent growth. They often present several therapeutic challenges because of their rarity, relatively late presentation and anatomical location, often in close relationship with several important structures in the retroperitoneal space. Extensive surgery is often required because of the intimate relationships with vital organs in the retroperitoneum. Retroperitoneal sarcomas frequently involve major vessels, originating from them or secondarily encase or invade them, requiring major vascular resections, with increasing morbidity. The main intervention that can increase the survival of patients with retroperitoneal tumors is radical resection. The involvement of large retroperitoneal vessels often makes impossible a radical intervention, usually because of the lack of an adequate material for ample and laborious vascular reconstruction. In this paper, a thorough search of the PubMed database was performed, to bring into the light the implications of vascular involvement in primary retroperitoneal tumors and the need of a strong cooperation between the urological or general surgeon and the vascular surgeon.

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Determining hemoglobin reference values in children and teenagers from Sibiu area

Cited by 8 publications

References 5 publications

Laboratory medicine in the era of precision medicine – dream or reality?

Laboratory medicine in the era of precision medicine – dream or reality?

Retroperitoneal Tumours - Treatment and Prognosis of Tumour Recurrence

Vascular Involvement in Primary Retroperitoneal Tumors

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