Determination of β-galactosidase activity in the intestinal tract of mice by ion-exchange high-performance liquid chromatography using ϵ-N-1-(1-deoxylactulosyl)-L-lysine as substrate

Analysis and biological properties of amino acid derivates formed by Maillard reaction in foods

“…A selective liquid chromatography (LC)-MS procedure allowed the detection and quantification of lactulosyllysine after complete enzymatic hydrolysis in milk samples [48]. One of the main problems related to the direct quantification of lactulosyl-lysine and other Amadori compounds is the lack of a pure standard [35,49]. The synthetic strategies proposed so far are rather time-consuming and do not yield a consistent rate of pure Amadori compound.…”

Convenient Synthesis of Lactuloselysine and Its Use for LC-MS Analysis in Milk-like Model Systems

“…One of the problems related to the direct quantification of lactuloselysine is the lack of a pure standard. In fact, the synthetic strategies proposed so far (Schreuder and Welling, 1983;Henle et al, 1991) are rather timeconsuming and do not yield a consistent rate of pure Amadori compound.…”