Determination of trace formaldehyde in blood plasma by resonance fluorescence technology

Wang, Yongsheng; Xuan, Tan; Xue, Jiaying; Li, Gui-Rong; Shi, Lin-Fei; Hong-mei, Yang; Liu, Lu; Zhou, Bin; Xiao, Xilin

doi:10.1016/j.aca.2011.02.030

Cited by 17 publications

(3 citation statements)

References 31 publications

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“…The mostly used method for formaldehyde detection are based on that the detection reagent and formaldehyde can form a speci c derivative under certain conditions, and formaldehyde can be detected by detrmination of the derivative at under special experimental conditions. Up to now spectrophotometer, high performance liquid chromatography, gas chromatography, electrochemical analysis, and other methods have been used to analyse formaldehyde content [7][8][9][10][11][12][13]. For instance, Nascimento et al devised a method for in-line dispersive liquid-liquid microextraction using pulsed streams and spectrophotometric determination of formaldehyde in milk.…”

Section: Introductionmentioning

confidence: 99%

A Novel Fluorescent and Colorimetric Method for the Determination of Formaldehyde Based on Albumin Nanoparticles-Polyethyleneimine-Ag+ Ion Nanohybrids

Pang,

Zhong,

Zhao

et al. 2023

J Fluoresc

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Formaldehyde is a common aldehydes in the environment. As a carcinogenic substances, high dose exposure may lead to poisoning and death. Long-term exposure to low doses of formaldehyde can also do great harm to human skin, respiratory organs and human immune system. Therefore, it is necessary to develop a method to detect formaldehyde content in real time. In this paper, bovine serum protein was used as the main raw material to prepare uorescence protein nanoparticles (BSA NPs). The prepared BSA NPs were combined with polyethylenimide (PEI) and silver ion (Ag + ) for further determination of formaldehyde content at room temperature. The particle size, potential, uorescence and absorbance properties of BSA NPs, BSA NPs combined with Ag + ions (BSA NPs-Ag), and BSA NPs combined with PEI and Ag + ions complex (BSA NPs-PEI-Ag) were studied and characterized. In this paper, based on the BSA NPs-PEI-Ag system, a new uorescent and colorimetric method for the determination of formaldehyde was established in the range of 0-1.92 mg•mL − 1 . Moreover, it was found that semi-quantitative visual detection of formaldehyde content could also be realized based on the color change of the solution.

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Section: Introductionmentioning

confidence: 99%

A Novel Fluorescent and Colorimetric Method for the Determination of Formaldehyde Based on Albumin Nanoparticles-Polyethyleneimine-Ag+ Ion Nanohybrids

Pang,

Zhong,

Zhao

et al. 2023

J Fluoresc

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“…Formaldehyde (FA) is the simplest aldehyde and the concentration of FA in the blood ranges from 0.0127 to 2.28 μg/mL (1.9 to 5.4 mg/L; or 63–179 μM) (Wang et al, 2011; Kleinnijenhuis et al, 2013). FA can be found in food and beverages (likely the largest quantitative source of exogenous FA) and is metabolically derived (see Conklin et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Formaldehyde Induces Mesenteric Artery Relaxation via a Sensitive Transient Receptor Potential Ankyrin-1 (TRPA1) and Endothelium-Dependent Mechanism: Potential Role in Postprandial Hyperemia

et al. 2019

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Formaldehyde (FA), the smallest aldehyde, is generated endogenously, and is widespread in the environment in foods, beverages and as a gas phase product of incomplete combustion. The main metabolite of FA, formate, was increased significantly in murine urine (∼3×) after overnight feeding. Because feeding increases mesenteric blood flow, we explored the direct effects of FA in isolated murine superior mesenteric artery (SMA). Over the concentration range of 30–1,200 μM, FA strongly and reversibly relaxed contractions of SMA induced by three different agonists: phenylephrine (PE), thromboxane A 2 analog (U46,619) and high potassium (60K, 60 mM K + ). Formate (to 1.5 mM) induced a modest relaxation. FA (>1,500 μM) irreversibly depressed vascular function in SMA indicating vasotoxicity. The sensitivity (EC 50 ) but not the efficacy (% relaxation) of FA-induced relaxations was dependent on blood vessel type (SMA << aorta) and contractile agonist (PE, EC 50 = 52 ± 14 μM; U46,619, EC 50 = 514 ± 129 μM; 60K, EC 50 = 1,093 ± 87 μM). The most sensitive component of FA vasorelaxation was within physiological levels (30–150 μM) and was inhibited significantly by: (1) mechanically impaired endothelium; (2) Nω-Nitro-L-arginine methyl ester hydrochloride (L-NAME); (3) transient receptor potential ankyrin-1 (TRPA1) antagonist (A967079); (4) guanylyl cyclase (GC) inhibitor (ODQ); and, (5) K + channel inhibitor (BaCl 2 ). A similar mechanism of SMA vasorelaxation was stimulated by the TRPA1 agonist cinnamaldehyde. Positive TRPA1 immunofluorescent staining and gene-specific sequence were present in SMA but not in aorta. These data indicate FA, but not formate, robustly relaxes SMA via a sensitive TRPA1- and endothelium-dependent mechanism that is absent in aorta. Thus, as FA levels increase with feeding, FA likely contributes to the physiological reflex of post-prandial hyperemia via SMA vasodilatation.

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“…Spectrophotometric techniques have been used to analyse rain water, mainstream smoke and tips of smoked cigarettes, using N,N-diethyl-p-phenylenediamine [33]; and paper and cardboard food packaging materials [34] and fish samples [35], derivatizing with 2,4pentanedione. Other analytical techniques such as excitation-emission matrix fluorescence spectroscopy (EEM) have been chosen by different authors for the analysis of food samples, using as derivatizing agent pyronine in the presence of phosphoric acid and sodium iodate [36] or with cyclohexane-1,3-dione [37] or with n-propylamine [38]; and blood plasma samples with pyronine in the presence of sulphuric acid and potassium bromate [39].…”

Section: Introductionmentioning

confidence: 99%

Kinetic models of migration of melamine and formaldehyde from melamine kitchenware with data of liquid chromatography

Sanllorente

Ortiz

2019

Journal of Chromatography A

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Determination of trace formaldehyde in blood plasma by resonance fluorescence technology

Cited by 17 publications

References 31 publications

A Novel Fluorescent and Colorimetric Method for the Determination of Formaldehyde Based on Albumin Nanoparticles-Polyethyleneimine-Ag+ Ion Nanohybrids

A Novel Fluorescent and Colorimetric Method for the Determination of Formaldehyde Based on Albumin Nanoparticles-Polyethyleneimine-Ag+ Ion Nanohybrids

Formaldehyde Induces Mesenteric Artery Relaxation via a Sensitive Transient Receptor Potential Ankyrin-1 (TRPA1) and Endothelium-Dependent Mechanism: Potential Role in Postprandial Hyperemia

Kinetic models of migration of melamine and formaldehyde from melamine kitchenware with data of liquid chromatography

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