Determination of tiopronin based on the enhancement of Ru(bpy) 3 2+ co-reactant electrochemiluminescence

Determination of tiopronin content in drug by copper(I)-cuproine spectrophotometry

“…In comparison to literature reports [3][4][5][6][7][8][9][10], the proposed method does not need complicated or expensive instrument, and the procedure of proposed method is simple and convenient.…”

“…Therefore, the determination of tiopronin content is of great importance. Up to now, spectrophotometry [1][2], kinetic spectrophotometry [3][4], flow injection [5][6], chemiluminescence [7], electrochemiluminescence [8], LC-MS/MS [9] and LC-ESI-MS [10] have been used to determinate the content of TPN. In these literature, spectrophotometry is a commonly used method owing to its simplicity, rapidity and cheap instrument.…”

“…In these literature, spectrophotometry is a commonly used method owing to its simplicity, rapidity and cheap instrument. In the literatures [3][4][5][6][7][8][9][10], complicated or expensive instruments are required, so the use of these methods is limited. The hydrosulfuryl(-SH) in tiopronin can quantitatively reduce Cu 2+ to Cu + , Cu + react with cuproine to form copper(І)cuproine amaranth complex in the condition of pH=5.0.…”

Exploring the electrochemiluminescent behavior of procaterol hydrochloride in the presence of Ru(bpy)32+ and its analytical application in pharmaceutical preparation

“…Electrochemiluminescence (ECL) has attracted significant attention over the past several decades due to its high sensitivity, low cost and relatively short analysis time compared with other techniques . The Ru(bpy) 3 2+ /coreactant ECL system is the most widely used in ECL research because of its strong luminescence and wide linear range . Although Cai et al .…”