Determination of the Trace Element Composition of Human Nails

Савинов, С. С.; Sharypova, R. M.; Drobyshev, A. I.

doi:10.1134/s1061934820030168

Cited by 7 publications

(5 citation statements)

References 22 publications

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“…The concentrations of Cd and Ni in our study were higher than levels reported in Russia [ 36 ], Thailand [ 37 ], Nigeria [ 7 ], India [ 43 ], Sweden [ 44 ], but lower than those in Malaysia [ 40 ] ( Table 5 ). It has been reported that a single cigarette contains about 1–2 µg of Cd that could be inhaled as 70% of the participants were smokers ( Table 1 ).…”

Section: Discussioncontrasting

confidence: 79%

Assessment and Exposure Analysis of Trace Metals in Different Age Groups of the Male Population in Southern Punjab, Pakistan

Hussain,

Khanam,

Ullah

et al. 2023

Toxics

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In developing countries, like Pakistan, the pursuit of urbanization and economic development disrupts the delicate ecosystem, resulting in additional biogeochemical emissions of heavy metals into the human habitat and posing significant health risks. The levels of these trace elements in humans remain unknown in areas at higher risk of pollution in Pakistan. In this investigation, selected trace metals including Copper (Cu), Chromium (Cr), Lead (Pb) Cadmium (Cd), Cobalt (Co), Nickel (Ni), and Arsenic (As) were examined in human hair, urine, and nail samples of different age groups from three major cities (Muzaffargarh, Multan, and Vehari) in Punjab province, Pakistan. The results revealed that the mean concentrations (ppm) of Cr (1.1) and Cu (9.1) in hair was highest in Muzaffargarh. In urine samples, the mean concentrations (μg/L) of Co (93), As (79), Cu (69), Cr (56), Ni (49), Cd (45), and Pb (35) were highest in the Multan region, while As (34) and Cr (26) were highest in Vehari. The mean concentrations (ppm) of Ni (9.2), Cr (5.6), and Pb (2.8), in nail samples were highest in Vehari; however, Multan had the highest Cu (28) concentration (ppm). In urine samples, the concentrations of all the studied metals were within permissible limits except for As (34 µg/L) and Cr (26 µg/L) in Vehari. However, in nail samples, the concentrations of Ni in Multan (8.1 ppm), Muzaffargarh (9 ppm), Vehari (9.2 ppm), and Cd (3.69 ppm) in Muzaffargarh exceeded permissible limits. Overall, the concentrations of metals in urine, nail, and hair samples were higher in adults (39–45 age group). Cr, Cu, and Ni revealed significantly higher concentrations of metals in hair and water in Multan, whereas As in water was significantly (p < 0.001) correlated with urinary As in Multan, indicating that the exposure source was region-specific.

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Section: Discussioncontrasting

confidence: 79%

Assessment and Exposure Analysis of Trace Metals in Different Age Groups of the Male Population in Southern Punjab, Pakistan

Hussain,

Khanam,

Ullah

et al. 2023

Toxics

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“…To assess elemental status, researchers have employed various biological matrices such as blood, urine, and serum. However, this review focuses on hair mineral analysis (HMA) as a diagnostic tool for ASD [6,7].…”

Section: Autism Spectrum Disorder (Asd)mentioning

confidence: 99%

Chemical Elements in Hair and Their Association with Autism Spectrum Disorder: A Comprehensive Systematic Review

Chojnacka,

Mikulewicz

2023

Pollutants

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Background: Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with increasing prevalence. This review aims to systematically investigate the relationship between the levels of toxic and trace elements in hair and the occurrence of ASD. Methods: Original articles reporting trace element levels in hair were included. A comprehensive search was conducted in databases such as Medline (via PubMed), Scopus, Web of Science, and Google Scholar, covering publications from 1 January 2000, to 2 January 2023. Keywords including “hair element analysis”, “trace elements”, and “autism”, were utilized in the search. Results: A direct comparison of the data was not possible due to the variety of methodologies observed in the available studies, including variations in sample sizes and analytical procedures. Conclusions: Exposure to toxic elements, notably Mercury (Hg) and Lead (Pb), which act as neurotoxicants, was found to be associated with the pathogenesis of ASD. Furthermore, a significant correlation was identified between the Zinc (Zn) to Copper (Cu) ratio and ASD.

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“…In assessing the elemental status of a human, various biological matrices can be used: blood, urine, serum and blood plasma, saliva, nails or hair [7] [8].…”

Section: Autism Spectrum Disorder (Asd)mentioning

confidence: 99%

Hair Trace Elements in Children With Autism Spectrum Disorders: Systematic Literature Review

Mikulewicz

Chojnacka

2021

Preprint

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(1) Background: The aim of this work was to systematically review the literature on the relation between the levels of elements in hair (toxic elements and trace elements) on the occurrence of autism spectrum disorder. (2) Methods: Search strategy and study selection: Original articles were included if they met the including criteria that report the trace element levels in hair. The following databases were screened: Medline (via PubMed), Scopus, Web of Science, Google Scholar (from 2000.01.01 to 2020.11.11). The main search terms used were “hair element analysis and trace elements and autism”. (3) Results: The papers available describe results of studies undertaken with the use of different methodology: diversified size of experimental groups, different sampling and analytical techniques. Therefore direct comparison of the results is not informative. (4) Conclusions: It was found that pathogenesis of autism spectrum disorder was associated with the exposure to toxic elements (e.g. Hg and Pb) which act as neurotoxicants. Also, the relation between some microelements seem to be significant, in particular the ratio Zn/Cu. Higher level of zinc and level levels of copper play the protectory role.

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Determination of the Trace Element Composition of Human Nails

Cited by 7 publications

References 22 publications

Assessment and Exposure Analysis of Trace Metals in Different Age Groups of the Male Population in Southern Punjab, Pakistan

Assessment and Exposure Analysis of Trace Metals in Different Age Groups of the Male Population in Southern Punjab, Pakistan

Chemical Elements in Hair and Their Association with Autism Spectrum Disorder: A Comprehensive Systematic Review

Hair Trace Elements in Children With Autism Spectrum Disorders: Systematic Literature Review

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