Determination of the antioxidant, antimicrobial and anticancer properties of the honey phenolic extract of five different regions of Bingöl province

Kaya, Bülent; Yıldırım, Adem

doi:10.1007/s13197-020-04783-x

Cited by 13 publications

(9 citation statements)

References 28 publications

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“…Acacia honey also exhibited anticancer activity against MCF-7 at a concentration of 5.5% v/v [105]. Beside HCT-1 and MCF-7, honey (0.5 to 1 mg/mL) was also reported to inhibit the growth of PC-3, a prostate cancer cell model [106].…”

Section: Anticancer Properties Of Bee Productsmentioning

confidence: 97%

Pharmaceutical Prospects of Bee Products: Special Focus on Anticancer, Antibacterial, Antiviral, and Antiparasitic Properties

et al. 2021

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Bee products have long been used in traditional healing practices to treat many types of disorders, including cancer and microbial-related diseases. Indeed, several chemical compounds found in bee products have been demonstrated to display anticancer, antibacterial, antiviral, and antiparasitic properties. With the improvement of research tools and in view of recent advances related to bee products, this review aims to provide broad yet detailed insight into the pharmaceutical prospects of bee products such as honey, propolis, bee pollen, royal jelly, bee bread, beeswax, and bee venom, in the domain of cancer and infectious disease management. Available literature confirms the efficacy of these bee products in the alleviation of cancer progression, inhibition of bacterial and viral proliferation, and mitigation of parasitic-related symptoms. With such potentials, bioactive components isolated from the bee products can be used as an alternative approach in the long-run effort to improve humans’ health at a personal and community level.

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Section: Anticancer Properties Of Bee Productsmentioning

confidence: 97%

Pharmaceutical Prospects of Bee Products: Special Focus on Anticancer, Antibacterial, Antiviral, and Antiparasitic Properties

et al. 2021

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“…Honey is called ‘medical-grade honey’ because of its antibacterial activity, use in several medical treatments, such as diabetes, and promotion of human health as a functional food [ 10 ]. The use of honey in the treatment of diabetes mellitus was confirmed by several studies (e.g., [ 8 , 9 , 11 , 12 , 13 , 14 , 15 , 16 ]). For the potential role of honey in managing glycemia (human blood sugar), honey as a sweetener could be added to food, such as yogurt, which could be consumed daily for chronic diseases [ 17 , 18 ].…”

Section: Introductionmentioning

confidence: 79%

Functional Yogurt Fortified with Honey Produced by Feeding Bees Natural Plant Extracts for Controlling Human Blood Sugar Level

Prokisch

El-Ramady

Daróczi³

et al. 2022

Plants

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The human blood sugar level is important and should be controlled to avoid any damage to nerves and blood vessels which could lead to heart disease and many other problems. Several market-available treatments for diabetes could be used, such as insulin therapy, synthetic drugs, herbal drugs, and transdermal patches, to help control blood sugar. In a double-blind human study, four kinds of honey from bees fed on acacia, sea buckthorn, chlorella alga, and green walnut extracts were used in fortifying yogurt for controlling human blood sugar. The impact of a previously fortified honey was investigated on blood levels and other parameters of healthy individuals in a human study with 60 participants. The participants received 150 mL of yogurt mixed with 30 g of honey every morning for 21 days. Before and after the study period, the basic blood parameters were tested, and the participants filled out standardized self-report questionnaires. Acacia honey was the traditional honey used as a control; the special honey products were produced by the patented technology. The consumption of green walnut honey had a significant effect on the morning blood sugar level, which decreased for every participant in the group (15 people). The average blood sugar level at the beginning in the walnut group was 4.81 mmol L−1, whereas the value after 21 days was 3.73 mmol L−1. The total decrease level of the individuals was about 22.45% (1.08 mmol L−1). Concerning the sea buckthorn and chlorella alga-based honey product groups, there was no significant change in the blood sugar level, which were recorded at 4.91 and 5.28 mmol L−1 before treatment and 5.28 and 5.07 mmol L−1 after, respectively. In the case of the acacia honey group, there was a slight significant decrease as well, it was 4.77 mmol L−1 at the beginning and 4.27 mmol L−1 at the end with a total decrease rate of 10.48%. It could thus be concluded that the active ingredients of green walnut can significantly decrease the blood sugar level in humans. This study, as a first report, is not only a new innovative process to add herbs or healthy active ingredients to honey but also shows how these beneficial ingredients aid the honey in controlling the human blood sugar level.

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“…The TPC and TFC of honey from China, USA, Brazil, New Zealand and Saudi Arabia are 56.32-246.21 mg gallic acid equivalents (GAE) g −1 and 20-2400 mg quercetin equivalents (QE) g −1 , respectively. 40 The concentration of phenolics in honey varies with flower type, 14 geography origin 41 and maturity. 18 Recently, studies have reported TPC in honey of northern Portugal as 22.61-72.77 mg GAE 100 g −1 .…”

Section: Mineralsmentioning

confidence: 99%

Composition, functional properties and safety of honey: a review

Wang

Lin

et al. 2023

J Sci Food Agric

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Honey has been used not only as a food source but also for medicinal purposes. Recent studies have indicated that honey exhibits antioxidant, hepatoprotective, hypolipidemic, hypoglycemic and anti‐obesity properties, as well as anticancer, anti‐atherosclerotic, hypotensive, neuroprotective and immunomodulatory activities. These health benefits of honey could be attributed to its wide range of nutritional components, including polysaccharides and polyphenols, which have been proven to possess various beneficial properties. It is notable that the composition of honey can also be affected by nectar, season, geography and storage condition. Moreover, the safety of honey requires caution to avoid any potential safety incidents. Therefore, this review aims to provide recent research regarding the chemical composition, biological activities and safety of honey, which might be attributed to comprehensive utilization of honey. © 2023 Society of Chemical Industry.

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Determination of the antioxidant, antimicrobial and anticancer properties of the honey phenolic extract of five different regions of Bingöl province

Cited by 13 publications

References 28 publications

Pharmaceutical Prospects of Bee Products: Special Focus on Anticancer, Antibacterial, Antiviral, and Antiparasitic Properties

Pharmaceutical Prospects of Bee Products: Special Focus on Anticancer, Antibacterial, Antiviral, and Antiparasitic Properties

Functional Yogurt Fortified with Honey Produced by Feeding Bees Natural Plant Extracts for Controlling Human Blood Sugar Level

Composition, functional properties and safety of honey: a review

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