Determination of tacrolimus in human whole blood in kidney transplant recipients using a rapid and specific LC–MS/MS method
Tran Ba Hieu,
Nguyen Manh Dung,
Pham Quoc Toan
et al.
Abstract:ObjectiveTo develop and validate an LC‐M/SMS method for the determination of tacrolimus in human whole blood.MethodThe LC–MS/MS method for the determination of tacrolimus in whole blood was developed and validated according to the guidelines. Concentrations of TAC in 100 kidney transplant patients measured by LC–MS/MS were compared with CMIA using correlation analysis and Bland–Altman plots.ResultsThe method had a total chromatographic run time of 5 min. The calibration curves were linear over the range of 0.5… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.