Determination of successful reperfusion after thrombolysis for acute myocardial infarction. A noninvasive method using ultrasonic tissue characterization that can be applied clinically

Caracterização tecidual ultra-sônica em síndromes coronarianas agudas

“…Scar delimitation with deposition of collagen requires a time period longer than four weeks of delay between the onset of symptoms and assessment. Since inclusion criteria in the present study required the absence of previous ischemic events or of any other factors that would involve myocardial structural damage -such as diabetes mellitus -nondifferentiation between the groups was not unexpected, and is in agreement with studies published elsewhere [8][9][10][15][16][17] . IBS variation amplitude changes are reported much earlier, and are more easily subject to documentation due to their ultrasonic tissue characterization.…”

Detection of cardiac sarcoidosis using cardiac markers and myocardial integrated backscatter

“…As mentioned previously, cyclic variation of integrated backscatter has been shown to be significantly reduced under various pathophysiologic conditions [12][13][14][15][16][17][18][19][20]. Although the mechanisms responsible for the phenomenon have not been fully elucidated, several factors, including regional myocardial contractile function, orientation of myocardial fibers, and structural changes of the myocardium, have been suggested to contribute to the changes in integrated backscatter cyclic variation.…”

“…This technique provides a novel approach for defining the physical state of cardiac muscle tissue that complements the assessment of ventricular wall motion and chamber dimensions by conventional two-dimensional echocardiography [12]. Recent studies have demonstrated that myocardial tissue characterization with integrated backscatter can be used to evaluate various pathologic conditions, such as ischemic/reperfusion injury [12][13][14], hypertrophied myocardium [15,16], dilated cardiomyopathy [17,18], diabetic heart disease [19], or cardiac amyloidosis [20]. We previously reported that the magnitude of integrated backscatter cyclic variations was significantly smaller in a patient with cardiac sarcoidosis [21].…”

Detection of TIMI-3 Flow Before Mechanical Reperfusion With Ultrasonic Tissue Characterization in Patients With Anterior Wall Acute Myocardial Infarction

“…Recently, Hancock et al 14 reported that CV of IBS measured 90 minutes after thrombolysis detects successful coronary reperfusion in the patients with AMI. The present study demonstrated that spontaneous reperfusion with TIMI-3 flow also could elicit similar quick recovery of CV, whereas TIMI-2 flow was not enough for the recovery of CV.…”