Determination of stoichiometry and equilibrium constants of complexes of tyrosine with cyclodextrins by time-resolved fluorescence spectroscopy and global analysis of fluorescence decays

Wiczk, Wiesław; Mrozek, Justyna; Szabelski, Mariusz; Karolczak, Jerzy; Guzow, Katarzyna; Malicka, Joanna

doi:10.1016/s0009-2614(01)00476-6

Cited by 12 publications

(5 citation statements)

References 24 publications

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“…These results can be explained in terms of the coexistence of two emitting individual species with different fluorescence lifetimes, and support the use of a global analysis 32. The measured fluorescence intensity decay for each concentration of CD was analyzed simultaneously assuming a kinetic model, in which fluorescence lifetimes were global parameters 33. The use of a global fit to a double exponential function reveals fluorescence lifetimes equal to τ 1 = 1.8 and τ 2 = 1.0 ns with a global $\chi _{\rm R}^2 $ = 1.053 (Fig.…”

Section: Resultssupporting

confidence: 54%

Neonatal rhabdomyoma causing right ventricular inflow obstruction with duct‐dependent pulmonary blood flow: Successful stenting of PDA

Ilina

Jaeggi

Lee

2007

Cathet Cardio Intervent

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We describe an infant with the antenatal diagnosis of a large intracardiac rhabdomyoma causing tricuspid inflow obstruction. Postnatal cyanosis and arterial hypoxemia prompted commencement of intravenous prostaglandin E1 with immediate improvement in saturations. Clinical and genetic testing confirmed diagnosis of tuberous sclerosis. To secure ductal patency, two tandem coronary stents were implanted via an antegrade approach. Several episodes of long RP atrio-ventricular re-entrant tachycardia were observed. At 7½ months of age, the tumor was no longer obstructive to tricuspid inflow, ductal flow was highly restrictive and there was no recurrence of supraventricular tachycardia. ' 2007 Wiley-Liss, Inc.Key words: rhabdomyoma; tricuspid inflow obstruction; stent implantation; patent arterial duct; SVT CASE REPORT A female baby was born at term by vaginal delivery to a healthy 33-year-old mother who had one previous miscarriage. There was no family history of tuberous sclerosis (TS). Surveillance obstetrical ultrasound scans at 12, 18, and 22 weeks gestation were normal. At 36 weeks gestation, polyhydramnios, and a cardiac mass were detected. The fetal echocardiogram revealed multiple homogeneous well circumscribed tumors within the myocardial wall. The largest mass was attached to the tricuspid valve and measured 1.3 3 1 cm 2 ( Fig. 1A and B). There was tricuspid inflow acceleration to a peak velocity of 126 cm/s and abnormal inferior and superior vena caval Doppler flow patterns with increased A-wave reversal consistent with right ventricular inflow obstruction. Rhabdomyomas associated with TS were quoted as most likely diagnosis.No resuscitation was required at birth. Birth weight was 2.8 kg. Hyperoxia test at 1 hr of age demonstrated a preductal PaO 2 of 80 mmHg. At 3 hr of age, cyanosis with a transcutaneous oxygen saturation of 82% in room air prompted commencement of prostaglandin E1 (alprostadil) infusion with immediate improvement in oxygen saturations to 95%. Neonatal examination was unremarkable except an ejection systolic murmur at the left upper sternal border. No dysmorphic features or skin lesions were found.Electrocardiogram on admission demonstrated atrial enlargement, right ventricular hypertrophy, and no preexcitation. The postnatal echocardiogram confirmed presence of multiple rhabdomyomas in the right and left ventricular free wall, interventricular septum, and left atrial appendage. The largest tumor (Fig. 1C and D) was attached to the atrial surface of anterior tricuspid leaflet causing severe tricuspid inflow obstruction and right to left shunt across the patent foramen ovale. The rest of the cardiovascular anatomy was normal and there was a patent ductus arteriosus (PDA).

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Section: Resultssupporting

confidence: 54%

Neonatal rhabdomyoma causing right ventricular inflow obstruction with duct‐dependent pulmonary blood flow: Successful stenting of PDA

Ilina

Jaeggi

Lee

2007

Cathet Cardio Intervent

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show abstract

“…32 The measured fluorescence intensity decay for each concentration of CD was analyzed simultaneously assuming a kinetic model, in which fluorescence lifetimes were global parameters. 33 The use of a global fit to a double exponential function reveals fluorescence lifetimes equal to t 1 ¼ 1.8 and t 2 ¼ 1.0 ns with a global x 2 R ¼ 1.053. (Fig.…”

Section: Photophysical Propertiesmentioning

confidence: 99%

Complexation and Chiral Drug Recognition of an Amphiphilic Phenothiazine Derivative with β‐Cyclodextrin

Guerrero‐Martínez

Montoro

Viñas

et al. 2008

Journal of Pharmaceutical Sciences

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“…Amino substituted isoquinolines are widely used in the medical field of research [12][13]. 1-Aminoisoquinoline is used in the synthesis and design of orally active thrombin inhibitors.…”

Section: Introductionmentioning

confidence: 99%

Investigation on association behavior between 1-Aminoisoquinoline and β-Cyclodextrin in solution and solid state

Rajamohan¹,

Nayaki

Swaminathan

2016

Journal of Molecular Liquids

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Determination of stoichiometry and equilibrium constants of complexes of tyrosine with cyclodextrins by time-resolved fluorescence spectroscopy and global analysis of fluorescence decays

Cited by 12 publications

References 24 publications

Neonatal rhabdomyoma causing right ventricular inflow obstruction with duct‐dependent pulmonary blood flow: Successful stenting of PDA

Neonatal rhabdomyoma causing right ventricular inflow obstruction with duct‐dependent pulmonary blood flow: Successful stenting of PDA

Complexation and Chiral Drug Recognition of an Amphiphilic Phenothiazine Derivative with β‐Cyclodextrin

Investigation on association behavior between 1-Aminoisoquinoline and β-Cyclodextrin in solution and solid state

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