In recent years, due to the increasingly powerful functions of tablets, more and more people have used tablets. The failure of the screen caused by debonding failure between the screen and the case of the tablet due to drops will affect the normal use of the tablet. However, there have been few studies on the debonding methods of the screen and the case of the tablet, as well as the factors influencing the debonding between the screen and the case of the tablet. Numerical analysis software was used in this paper to simulate the iPad Air (Air) drop process, and the cohesive zone model and tiebreak contact were used to simulate the debonding process between the screen and case of the Air tablet, respectively. When the results are compared to the experiments, the results show that the cohesive zone model is superior. The effects of various rounded corner radii, drop postures in the XY plane, materials of the outer case, and strain rates of PC/ABS on the localized debonding between the outer case and outer glass of the Air during the drop process were investigated. The degree of debonding between the Air model’s outer case and outer glass is defined by t, which is the ratio of the area of the deleted cohesive elements to the total area of the cohesive elements. The results show that the rounded corner radius and the strain rate of PC/ABS have less influence on t; the t of the Air model dropped at 45° in the XY plane is 37.7% of that dropped at 0° and 90°; and the t of the Air model with glass as the outer case material is 48% of that with aluminum alloy as the outer case material. These studies serve as a foundation for tablet design and material selection.