Determination of stability constants of metal complexes with IC-ICP-MS

Elemental labelling combined with liquid chromatography inductively coupled plasma mass spectrometry for quantification of biomolecules: A review

“…influences on composition of metalloproteins or transmetallation of elemental labels). These separation methods comprise size exclusion chromatography (SEC) [9–14,126] or ion exchange chromatography (IEC) [15–18] , which are highly compatible to ICP-MS detection and were implemented in one or multidimensional separation schemes [19] . Recent developments of elemental speciation analysis are summarized by Harrington et al [20] .…”

Atomic spectrometry update. Industrial analysis: metals, chemicals and advanced materials

“…The authors described the technique as being relatively simple and rapid as well as being of low cost. In the last application of note in this part of the review, Xing and Beauchemin have continued their determination of stability constants of metal complexes using ICP-MS. 200 Previous publications had reported the determination of free metals and metal complexes by ion exchange separation followed by ICP-MS detection. A plot of log(peak area of complex/peak area of free metal) against log(total free EDTA concentration) for a series of solutions containing the analytes and a range of EDTA concentrations yielded straight lines, the intercepts of which corresponded to the stability constants.…”

Chromium speciation at trace level in potable water using hyphenated ion exchange chromatography and inductively coupled plasma mass spectrometry with collision/reaction interface

“…[17][18][19] In fact, some ion-exchange column with dual exchange capability is commercially available and was successfully utilized for speciation studies. 12,20,21 As will be demonstrated in this work, a simple guard column of such material with both cation and anion exchange capabilities can be used to achieve a quick quantitative separation of Cr(III) and Cr(VI).…”