Determination of some trace elements in the thyroid gland by INAA

Kvícala, J; Havelka, J; Zeman, Jakub; Nĕmec, J

doi:10.1007/bf02062052

Cited by 14 publications

(10 citation statements)

References 3 publications

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“…Values obtained for Cr, Fe, Hg, Rb, Sb, Sc, Se, and Zn contents in the normal human thyroid (Table 3) agree well with median of mean values reported by other researches [25][26][27][28][29][30][31][32][33][34][35]. The obtained means for Ag and Co were almost one order of magnitude lower median of previously reported means but inside the range of means (Table 3).…”

Section: Comparison With Published Datasupporting

confidence: 89%

“…The reliable data on TE mass fractions in normal human thyroid separately for female and male gland is apparently extremely limited. There are a few studies regarding TE content in human thyroid, using chemical techniques and instrumental methods [25][26][27][28][29][30][31][32][33][34][35]. However, the majority of these data are based on measurements of processed tissue and in many studies tissue samples are ashed before analysis.…”

Section: Introductionmentioning

confidence: 99%

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Possible Role of Inadequate Quantities of Intra-Thyroidal Cobalt, Rubidium and Zinc in the Etiology of Female Subclinical Hypothyroidism

Zaichick¹

2018

WHSJ

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Background: Subclinical hypothyroidism does affect fertility. The prevalence of subclinical hypothyroidism is 10-15 times more common in women than in men. Trace elements play important roles in thyroid function and fertility. Objective: The aim of this exploratory study was to evaluate whether significant differences of trace element contents exists between female and male thyroids and how they can be related to the etiology of subclinical hypothyroidism. Methods: Thyroid tissue levels of ten trace elements: silver, cobalt, chromium, iron, mercury, rubidium, antimony, scandium, selenium, and zinc were prospectively evaluated in 105 healthy persons (33 females and 72 males). Measurements were performed using instrumental neutron activation analysis with high resolution spectrometry of long-lived radionuclides. Tissue samples were divided into two portions. One was used for morphological study while the other was intended for trace element analysis. Results: It was found that content of cobaltin thyroid of females was significantly higher than that of males, while contents of rubidiumand zinc were lower. Conclusions: Inappropriate content of intra-thyroidal cobalt, rubidiumand zinc can be associated with the etiology of female subclinical hypothyroidism.

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Section: Comparison With Published Datasupporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Possible Role of Inadequate Quantities of Intra-Thyroidal Cobalt, Rubidium and Zinc in the Etiology of Female Subclinical Hypothyroidism

Zaichick¹

2018

WHSJ

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“…The reliable data on chemical element mass fractions in normal geriatric thyroid is apparently extremely limited. There are many studies regarding chemical element content in human thyroid, using chemical techniques and instrumental methods [25][26][27][28][29][30][31][32][33][34][35][36]. However, majority of the analytical methods currently used and validated for the determination of major and trace elements in thyroid and other human organs are based on techniques need in sample digestion.…”

Section: Current Trends In Biomedical Engineering and Biosciencesmentioning

confidence: 99%

Age-Related Changes of Ag, Co, Cr, Fe, Hg, Rb, Sb,Sc, Se, and Zn Contents in Intact Thyroid of Males Investigated by Neutron Activation Analysis

Zaichick¹

2017

CTBEB

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A prevalence of thyroid dysfunction is higher in the elderly as compared to the younger population. An excess or deficiency of trace element contents in thyroid plays important role ingoitro-and carcinogenesis of gland. The variation with age of the mass fraction of ten trace elements (Ag, Co, Cr, Fe, Hg, Rb, Sb, Sc, Se, and Zn) in intact (normal) thyroid of 62 males (mean age 35.9 years, range 2-80) was investigated by instrumental neutron activation analysis with high resolution spectrometry of long-lived radio nuclides. Mean values± standard error of mean for mass fractions (mg/kg, on dry-mass basis) of the trace elements studied were: Ag0.0156±0.

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“…The reliable data on chemical element mass fractions in normal geriatric thyroid is apparently extremely limited. There are multiple studies reporting chemical element content in human thyroid, using chemical techniques and instrumental methods [25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42]. However, majority of the analytical methods currently used and validated for the determination of major and trace elements in thyroid and other human organs are based on techniques requiring sample digestion.…”

Section: Introductionmentioning

confidence: 99%

Neutron Activation and X-Ray Fluorescent Analysis in Study of Association Between Age and Chemical Element Contents in Thyroid of Males

Zaichick

2018

OAJBEB

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Determination of some trace elements in the thyroid gland by INAA

Cited by 14 publications

References 3 publications

Possible Role of Inadequate Quantities of Intra-Thyroidal Cobalt, Rubidium and Zinc in the Etiology of Female Subclinical Hypothyroidism

Possible Role of Inadequate Quantities of Intra-Thyroidal Cobalt, Rubidium and Zinc in the Etiology of Female Subclinical Hypothyroidism

Age-Related Changes of Ag, Co, Cr, Fe, Hg, Rb, Sb,Sc, Se, and Zn Contents in Intact Thyroid of Males Investigated by Neutron Activation Analysis

Neutron Activation and X-Ray Fluorescent Analysis in Study of Association Between Age and Chemical Element Contents in Thyroid of Males

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