Determination of sodium and potassium in nanoliter volumes of biological fluids by furnace atomic absorption spectrometry

Nash, L; Peterson, Linda N.; Nadler, Steven P.; Levine, David Z.

doi:10.1021/ac00172a019

Cited by 13 publications

(4 citation statements)

References 11 publications

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“…The determination of cations in aqueous samples and human body fluids can be made by several techniques, for example, atomic absorption and ion chromatography [10,11]. Ion chromatography is a sensitive and well-tested separation technique, and no sample preparation is needed for condensate samples.…”

Section: Introductionmentioning

confidence: 99%

Optimization and validation of an ion chromatographic method for the simultaneous determination of sodium, ammonium and potassium in exhaled breath condensate

Svensson

Isacsson

Ljungkvist

et al. 2005

Journal of Chromatography B

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Section: Introductionmentioning

confidence: 99%

Optimization and validation of an ion chromatographic method for the simultaneous determination of sodium, ammonium and potassium in exhaled breath condensate

Svensson

Isacsson

Ljungkvist

et al. 2005

Journal of Chromatography B

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“…The analysis of these anions and cations in aqueous samples can be made by several techniques such as atomic absorption spectrometry (AAS) [1][2][3], inductively coupled plasma-atomic emission spectrometry (ICP-AES) [4,5], flame photometry [4] or ion selective electrode methods [5][6][7][8]. While useful, these analytical methods are capable of analysing only a single analyte at a time.…”

Section: Introductionmentioning

confidence: 99%

Comparison of liquid chromatography and capillary electrophoresis methods for quantification of sodium residuals

Briône

Herbots²,

Kottgen

et al. 2007

Journal of Pharmaceutical and Biomedical Analysis

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“…On-chip microfluidics is normally considered when working with ultrasmall volumes, especially when multiple steps are required, because it can be used not only to automate the steps but also to minimize or eliminate evaporation because the system is enclosed. [15][16][17] Other approaches to working with ultrasmall volumes involve working under conditions that prevent or minimize evaporation, such as mixing with a liquid having a high vapor pressure such as glycerine, [18][19][20] placing a sample under a protective layer of an immiscible fluid such as heptane or mineral oil, [21][22][23][24][25][26] or using a solvent-saturated environment. 20,27 When microdispensing is combined with methods of detection that are so fast that evaporation can be ignored, then an alternative approach for analyses on ultrasmall-volume scales is possible.…”

mentioning

confidence: 99%

Analysis in Ultrasmall Volumes: Microdispensing of Picoliter Droplets and Analysis without Protection from Evaporation

et al. 2003

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A new approach is reported for analysis of ultrasmall volumes. It takes advantage of the versatile positioning of a dispenser to shoot approximately 150-pL droplets of liquid onto a specific location of a substrate where analysis is performed rapidly, in a fraction of the time that it takes for the droplet to evaporate. In this report, the site where the liquid is dispensed carries out fast-scan cyclic voltammetry (FSCV), although the detection method does not need to be restricted to electrochemistry. The FSCV is performed at a microcavity having individually addressable gold electrodes, where one serves as working electrode and another as counter/pseudoreference electrode. Five or six droplets of 10 mM [Ru(NH(3))(6)]Cl(3) in 0.1 M KCl were dispensed and allowed to dry, followed by redissolution of the redox species and electrolyte with one or five droplets of water and immediate FSCV, demonstrating the ability to easily concentrate a sample and the reproducibility of redissolution, respectively. Because this approach does not integrate detection with microfluidics on the same chip, it simplifies fabrication of devices for analysis of ultrasmall volumes. It may be useful for single-step and multistep sample preparation, analyses, and bioassays in microarray formats if dispensing and changing of solutions are automated. However, care must be taken to avoid factors that affect the aim of the dispenser, such as drafts and clogging of the nozzle.

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Determination of sodium and potassium in nanoliter volumes of biological fluids by furnace atomic absorption spectrometry

Cited by 13 publications

References 11 publications

Optimization and validation of an ion chromatographic method for the simultaneous determination of sodium, ammonium and potassium in exhaled breath condensate

Optimization and validation of an ion chromatographic method for the simultaneous determination of sodium, ammonium and potassium in exhaled breath condensate

Comparison of liquid chromatography and capillary electrophoresis methods for quantification of sodium residuals

Analysis in Ultrasmall Volumes: Microdispensing of Picoliter Droplets and Analysis without Protection from Evaporation

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