Determination of selenium in foods by pseudo-cyclic neutron activation and anti-coincidence gamma-ray spectrometry

Zhang, W.; Chatt, A.

doi:10.1007/s10967-009-0238-9

Cited by 11 publications

(5 citation statements)

References 9 publications

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“…If several minutes to days are allowed to elapse between repetitions of these cycles, then the technique is called pseudo-cyclic INAA (PC-INAA). In the past, several CINAA and PC-INAA methods were developed in our laboratory for the determination of Se in various matrices (40–47) but not urine. In the study reported here, the short-lived nuclide 77m Se was applied for the first time, to the best of the authors’ knowledge, to the direct determination of Se in urine samples without any chemical separation.…”

Section: Discussionmentioning

confidence: 99%

Estimation of daily selenium intake by 3- to 5-year-old Japanese children based on selenium excretion in 24-h urine samples

Nakamura¹,

Fukushima

Hoshi

et al. 2019

J Nutr Sci

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To evaluate the daily Se intake of 3- to 5-year-old Japanese children, we used seventy-two urine samples collected from fifty-three children (twenty-seven male and twenty-six female) from two cities in Miyagi prefecture, Japan. For measuring low Se concentrations with high precision, accuracy and rapidity in the 24-h urine samples, we developed an instrumental neutron activation analysis (INAA) method, that is without any chemical separation, using the short-lived 77mSe (t1/2 = 17·4 s) nuclide. The estimated Se intake of the fifty-three children was 51·5 (sd 30·2) µg/d (geometric mean: 42·7 µg/d). Ten subjects (three male and seven female), successfully provided 24-h urine samples over two or three consecutive days; their Se intake was 37·4 (sd 5·9) µg/d. Based on the logarithmically transformed data of these ten subjects, the ratio of intra-/inter-individual variances of usual Se intake was 16·7 (28·0/1·7) and geometric mean was 27·7 µg/d. The 5th to 95th percentile of usual Se intake of these ten subjects was 17·5 to 40·4 µg/d, which ranged between the recommended dietary allowance and tolerable upper intake level of Se by the Dietary Reference Intakes for Japanese (2015).

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Section: Discussionmentioning

confidence: 99%

Estimation of daily selenium intake by 3- to 5-year-old Japanese children based on selenium excretion in 24-h urine samples

Nakamura¹,

Fukushima

Hoshi

et al. 2019

J Nutr Sci

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“…However, selenium can be harmful when regularly taken in amounts higher than those needed for good health. About two orders of magnitude higher levels of Se are known to cause toxic effects (Zhang and Chatt, 2009).…”

Section: Risks From Excessive Seleniummentioning

confidence: 99%

“…Selenium is an essential nutrient for humans and animals. However, selenium can be harmful when regularly taken in amounts higher than those needed for good health (Zhang and Chatt 2009). People receive the majority of their daily intake of selenium from eating food.…”

Section: Introductionmentioning

confidence: 99%

Feasibility of measuring selenium in humans usingin vivoneutron activation analysis

Tahir

Chettle²,

Byun³

et al. 2015

Physiol. Meas.

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Selenium (Se) is an element that, in trace quantities, plays an important role in the normal function of a number of biological processes in humans. Many studies have demonstrated that selenium deficiency in the body may contribute to an increased risk for certain neoplastic, cardiovascular, osseous, and nervous system diseases including retardation of bone formation. However, at higher concentrations Se is cytotoxic. For these reasons it is desirable to have a means of monitoring selenium concentration in humans.This paper presents the outcome of a feasibility study carried out for measuring selenium in humans using in vivo neutron activation analysis (IVNAA). In this technique a small dose of neutrons is delivered to the organ of interest, the neutrons are readily captured by the target nuclei, and the γ-rays given off are detected outside of the body. For the present study, human hand (bone) tissue equivalent phantoms were prepared with varying amounts of Se. These were irradiated by a low energy fast neutron beam produced by the (7)Li(p,n)(7)Be reaction employing the high beam current Tandetron accelerator. The counting data saved using a 4π NaI(TI) detection system were analyzed. The selenium was detected via the neutron capture reaction, (76)Se(n,γ)(77 m)Se, whereas calcium was detected through the (48)Ca(n,γ)(49)Ca reaction for the purpose of normalization of the Se signals to the calcium signals. From the calibration lines drawn between Se/Ca concentrations and Se/Ca counts ratio, the minimum detection limits (MDLs) were computed for two sets of phantoms irradiated under different irradiation parameters.In this study the optimized MDL value was determined to be 81 ng g(-1) (Se/phantom mass) for an equivalent dose of 188 mSv to the phantom. This MDL was found at least 10 times lower than the reported data on Se concentration measured in bone tissues. It was concluded that the NAA technique would be a feasible means of performing in vivo measurements of selenium in humans. Currently the data on in vivo measurement of selenium in humans are limited; the results of the present study would greatly contribute to the present data.

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“…The entire process repeats for a number of cycles [3,4]. In the case of sample with high dead time, a pseudo-cyclic NAA (PCNAA) technique was alternatively developed based on CNAA by adjusting the CNAA timing parameters [5][6][7][8], especially the waiting time between the repetitions of the irradiationdecay-counting cycles, which allowed to elapse in several minutes to days to reduce the dead time of spectrometer. Another alternative technique is a cumulative NAA, which was developed from irradiation and counting of a number of replicates of the same sample, the individual spectra are combined to generate a total spectrum [9,10].…”

Section: Introductionmentioning

confidence: 99%

Combination and optimization of the cyclic NAA modes at the Dalat research reactor for determination of selenium in biological materials using 77mSe

Tran

et al. 2016

J Radioanal Nucl Chem

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The combination and optimization of the cyclic modes in neutron activation analysis (NAA) at the Dalat research reactor were performed to determine short-lived nuclides. This work focused on determination of selenium in biological materials using 77m Se (T 1/2 = 17.4 s) as a case in point. The detection limit was significantly improved by a factor of 3-4 times in comparison with the conventional NAA. The precision was typically within the range of 4-6 % at the third or fourth cycle. It is a reliable technique for determination of selenium in biological materials at sub-ppm concentration levels.

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Determination of selenium in foods by pseudo-cyclic neutron activation and anti-coincidence gamma-ray spectrometry

Cited by 11 publications

References 9 publications

Estimation of daily selenium intake by 3- to 5-year-old Japanese children based on selenium excretion in 24-h urine samples

Estimation of daily selenium intake by 3- to 5-year-old Japanese children based on selenium excretion in 24-h urine samples

Feasibility of measuring selenium in humans usingin vivoneutron activation analysis

Combination and optimization of the cyclic NAA modes at the Dalat research reactor for determination of selenium in biological materials using 77mSe

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