Determination of selenium in blood components by X-ray emission spectrometry

Abstract

Sampling, storing, sample pretreatment, and experimental conditions for selenium (Se) determination in human serum, plasma, and whole blood by X-ray emission spectrometric (XRS) methods are described. Concentration levels in these biological fluids, found by this technique, are discussed and compared to values found by other techniques for the same healthy population group in the same area. XRS analysis of blood from patients with various pathological conditions is reviewed, with special attention to the relation of Se with the concentration level of other essential or nonessential trace elements.

Plasma selenium levels in healthy blood bank donors in the central-eastern part of Belgium

“…No difference was made in this review between plasma and serum, as done by most authors [25][26][27]. Only one publication [28] claimed that serum concentrations cannot be equated with plasma values.…”

Comparison of the serum selenium content of healthy adults living in the Antwerp region (Belgium) with recent literature data

“…No difference was made in this review between plasma and serum, as done by most authors [14,22,83,[131][132][133][134][135][136][137]. Meltzer et al [83] mentioned serum as well as plasma selenium in the abstract.…”

Selenium speciation in human body fluids†

“…40 We have also shown that previous selenium supplementation affects the retention of enriched stable isotopes of selenium in human subjects in New Zealand consuming diets low in selenium. 41 (iv) Robberecht and Deelstra 42 discussed various factors that influence blood selenium concentrations such as age, gender, smoking, drinking and race. We can document some of these effects but we do not know to what extent any of these factors affect individual selenoproteins and whether they affect different proteins in different ways.…”