Determination of risk factors affecting the in-hospital prognosis of patients with acute ST segment elevation myocardial infarction after percutaneous coronary intervention

Abstract

BackgroundTo determine the factors affecting the in-hospital prognosis of patients with acute ST segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI), and to establish its prognostic discriminant model.MethodsA total of 701 consecutive STEMI patients undergoing PCI were enrolled in this study. The patients were divided into two groups, good prognosis and poor prognosis, based on whether the patient had adverse outcomes (death or heart function ≥ grade III) at discharge. Demographic and basic clinical characteristics, diagnosis at admission (e.g., ventricular function, complications, or hyperlipidemia), and biomedical indicators (e.g., blood count, basal metabolism and biochemical composition, blood lipid and glucose levels, myocardial biomarkers, and coagulation) were collected and analyzed.ResultsWe determined 22 factors as risk factors for the in-hospital prognosis of STEMI patients after PCI: age, cardiac function during hospitalization, complications, history of diabetes mellitus, et al., among which the history of diabetes, uric acid, urea nitrogen, and activated partial thromboplastin time (APTT) were independent risk factors.ConclusionWe identified four independent risk factors for the in-hospital prognosis of STEMI patients after PCI and generated a prognostic model to predict the adverse outcomes of these patients.

Concomitant multi-vessel disease is associated with a lower procedural death rate in patients treated with percutaneous coronary interventions within the left main coronary artery (from the ORPKI registry)

“…A similar relationship was found for diabetes [24,25]. This relationship could be explained mainly due to the pathogenesis of atherosclerosis and higher frequency of MVD in patients with kidney failure and diabetes compared to those without kidney function impairment [24,25].…”

“…Previously published studies revealed that elevated creatinine level was associated with poor myocardial blood flow and with an increased risk of death during the one-year follow-up after emergency PCI procedures in patients with STEMI [23]. A similar relationship was found for diabetes [24,25]. This relationship could be explained mainly due to the pathogenesis of atherosclerosis and higher frequency of MVD in patients with kidney failure and diabetes compared to those without kidney function impairment [24,25].…”

Effect of a nurse-led individualized self-management program for Chinese patients with acute myocardial infarction undergoing percutaneous coronary intervention

“…waist/hip ratio, dietary patterns, apolipoproteins, psychosocial factors) have been found in recent years. 29 The effect of self-management intervention on these factors was not examined in our study. Future studies to examine the effects of the intervention on these risk factors are needed.…”

Estimated glomerular filtration rate as one of the main predictors of in-hospital mortality in Egyptian patients with ST elevation myocardial infarction: a two-year retrospective study

“…STEMI has high morbidity and mortality. Risk stratification is of extreme importance for better patient outcome [14]. Our goal was to test some of the previously reported predictors of mortality in STEMI patients in an Egyptian cohort.…”